Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		1.000 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1 		0.550 Biomarker disease CLINGEN
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		0.550 Biomarker disease CLINGEN
Entrez Id: 5605
Gene Symbol: MAP2K2
MAP2K2 		0.540 Biomarker disease CLINGEN
Entrez Id: 5921
Gene Symbol: RASA1
RASA1 		0.310 Biomarker disease CLINGEN
Entrez Id: 5922
Gene Symbol: RASA2
RASA2 		0.300 Biomarker disease CLINGEN
Entrez Id: 5500
Gene Symbol: PPP1CB
PPP1CB 		0.300 Biomarker disease CLINGEN
Entrez Id: 6237
Gene Symbol: RRAS
RRAS 		0.300 Biomarker disease CLINGEN
Entrez Id: 8216
Gene Symbol: LZTR1
LZTR1 		0.300 Biomarker disease CLINGEN
Entrez Id: 144568
Gene Symbol: A2ML1
A2ML1 		0.300 Biomarker disease CLINGEN
Entrez Id: 22808
Gene Symbol: MRAS
MRAS 		0.300 Biomarker disease CLINGEN
Entrez Id: 6655
Gene Symbol: SOS2
SOS2 		0.300 Biomarker disease CLINGEN
Entrez Id: 6016
Gene Symbol: RIT1
RIT1 		0.300 Biomarker disease CLINGEN
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		1.000 GeneticVariation disease CLINVAR Characterization of the phosphorylation sites and the surrounding amino acid sequences of the p21 transforming proteins coded for by the Harvey and Kirsten strains of murine sarcoma viruses. 6288698 1982
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		1.000 GeneticVariation disease CLINVAR Nucleotide sequence of the p21 transforming protein of Harvey murine sarcoma virus. 6287572 1982
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		1.000 GeneticVariation disease CLINVAR Nucleotide sequence of the oncogene encoding the p21 transforming protein of Kirsten murine sarcoma virus. 6287573 1982
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		1.000 GeneticVariation disease CLINVAR Ras p21 proteins with high or low GTPase activity can efficiently transform NIH/3T3 cells. 3004741 1986
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		1.000 GeneticVariation disease CLINVAR ras genes. 3304147 1987
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		1.000 GeneticVariation disease CLINVAR The ras gene family and human carcinogenesis. 3283542 1988
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		1.000 GeneticVariation disease CLINVAR rac, a novel ras-related family of proteins that are botulinum toxin substrates. 2674130 1989
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		1.000 CausalMutation disease CLINVAR Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumor progression. 2105486 1990
Entrez Id: 2006
Gene Symbol: ELN
ELN 		0.050 Biomarker disease BEFREE Given that elastic fiber degeneration was observed in the tissues with clinical symptoms, we speculate that a defect of elastic fibers, possibly relating to alternative splicing in the elastin gene or to defects in elastin microfibrils, might be involved in the pathogenesis of Costello syndrome. 8834040 1996
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		1.000 GeneticVariation disease CLINVAR Role of the switch II region in the conformational transition of activation of Ha-ras-p21. 10716188 2000
Entrez Id: 2006
Gene Symbol: ELN
ELN 		0.050 AlteredExpression disease BEFREE Costello syndrome with decreased gene expression of elastin in cultured dermal fibroblasts. 11146354 2000
Entrez Id: 2006
Gene Symbol: ELN
ELN 		0.050 Biomarker disease BEFREE Decreased elastin deposition and high proliferation of fibroblasts from Costello syndrome are related to functional deficiency in the 67-kD elastin-binding protein. 10712202 2000