Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.100 Biomarker phenotype BEFREE Not only the dose but the route of administration and the tissue in which the malignancy or toxicity develops are therefore very important in the interpretation of data from tumorigenesis or toxicity experiments involving P1-450 inducers such as polycyclic hydrocarbons. 7016519 1981
Entrez Id: 49
Gene Symbol: ACR
ACR
0.010 GeneticVariation phenotype BEFREE The results suggest that this phenotypic marker may be useful in identifying ACR gene carriers and in probing cellular controls of carcinogenesis. 7287208 1981
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.100 GeneticVariation phenotype BEFREE If similar enhancers exist in humans they may lead to increased transcription of the translocated c-myc gene and thus contribute to oncogenesis in Burkitt lymphoma. 6419124 1984
Entrez Id: 4613
Gene Symbol: MYCN
MYCN
0.100 Biomarker phenotype BEFREE This finding suggests that N-myc gene may have a primary role in the tumorigenesis of retinoblastoma. 6728001 1984
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.100 Biomarker phenotype BEFREE These changes are probably the result of somatic mutations that occurred during and after translocation, and may contribute to oncogenesis by allowing synthesis of an altered c-myc gene product. 6419122 1984
Entrez Id: 404663
Gene Symbol: LINC01194
LINC01194
0.060 AlteredExpression phenotype BEFREE Since we have mapped the low-oncogenic or nononcogenic Ad12 cyt mutants within the 19-kd tumor antigen-coding region, our results further indicate that the 19-kd tumor antigen also directly or indirectly plays an important role in tumorigenesis of Ad12. 6492253 1984
Entrez Id: 100188830
Gene Symbol: AD12
AD12
0.010 GeneticVariation phenotype BEFREE Since we have mapped the low-oncogenic or nononcogenic Ad12 cyt mutants within the 19-kd tumor antigen-coding region, our results further indicate that the 19-kd tumor antigen also directly or indirectly plays an important role in tumorigenesis of Ad12. 6492253 1984
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.100 Biomarker phenotype BEFREE As the transfectants acquire an indefinite life-span and anchorage independence they became transplantable tumor cells and showed many phenotypic changes suggesting a pleiotropic mechanism for the role of Ha ras in human carcinogenesis. 3975607 1985
Entrez Id: 1443
Gene Symbol: CSH2
CSH2
0.020 Biomarker phenotype BEFREE Linkage of human chorionic gonadotrophin and placental lactogen biosynthesis to trophoblast differentiation and tumorigenesis. 2991878 1985
Entrez Id: 1442
Gene Symbol: CSH1
CSH1
0.010 Biomarker phenotype BEFREE Linkage of human chorionic gonadotrophin and placental lactogen biosynthesis to trophoblast differentiation and tumorigenesis. 2991878 1985
Entrez Id: 2217
Gene Symbol: FCGRT
FCGRT
0.010 Biomarker phenotype BEFREE Since this region of chromosome has been shown to be nonrandomly involved in a number of T cell neoplasias, this assignment raises a number of interesting questions as to the possible involvement of the T cell receptor alpha chain genes in tumorigenesis. 3872924 1985
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 GeneticVariation phenotype BEFREE This gene shares structural and sequence homologies with the epidermal growth factor receptor (erb-B oncogene) and members of the src family of oncogenes, suggesting that alterations in the insulin receptor, resulting from chromosomal translocation, could lead to a role in tumorigenesis. 3943110 1986
Entrez Id: 3643
Gene Symbol: INSR
INSR
0.090 GeneticVariation phenotype BEFREE This gene shares structural and sequence homologies with the epidermal growth factor receptor (erb-B oncogene) and members of the src family of oncogenes, suggesting that alterations in the insulin receptor, resulting from chromosomal translocation, could lead to a role in tumorigenesis. 3943110 1986
Entrez Id: 5820
Gene Symbol: PVT1
PVT1
0.050 Biomarker phenotype BEFREE The significance of these results with respect to the role of pvt-1 in tumorigenesis is discussed. 3024964 1987
Entrez Id: 2526
Gene Symbol: FUT4
FUT4
0.010 Biomarker phenotype BEFREE These results demonstrate that the flat mucosa of patients with familial polyposis coli shows preneoplastic changes similar to those in the mucosa adjacent to carcinoma of sporadic cases, and that SSEA-1 is related to adenoma formation in the early stage of carcinogenesis in the colorectum. 2885160 1987
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.100 Biomarker phenotype BEFREE Efforts to reconstruct multistep tumorigenesis in cell culture have shown that two types of oncogenes (typified by HRAS and MYC) can cooperate to elicit complete transformation. 3132710 1988
Entrez Id: 573
Gene Symbol: BAG1
BAG1
0.100 AlteredExpression phenotype BEFREE The data suggest that the hap gene product may be a novel ligand-responsive regulatory protein whose inappropriate expression in liver may relate to the hepatocellular carcinogenesis. 2825037 1988
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
0.100 GeneticVariation phenotype BEFREE This report gives evidence that an amplified c-myc and a mutated N-ras gene are both present in this tumor cell line and provides support for the idea that co-operation of at least 2 activated cellular oncogenes is required for carcinogenesis. 3284824 1988
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.100 Biomarker phenotype BEFREE Our current data suggest that gamma rays worked as an initiator of carcinogenesis in normal human cells, giving rise to chromosome aberrations and immortality, and the Ha-ras oncogene played a role in the progression of the immortally transformed cell population to a neoplastic one showing enhanced colony formation in soft agar and tumorigenicity in nude mice. 3287150 1988
Entrez Id: 5915
Gene Symbol: RARB
RARB
0.100 AlteredExpression phenotype BEFREE The data suggest that the hap gene product may be a novel ligand-responsive regulatory protein whose inappropriate expression in liver may relate to the hepatocellular carcinogenesis. 2825037 1988
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.100 Biomarker phenotype BEFREE Efforts to reconstruct multistep tumorigenesis in cell culture have shown that two types of oncogenes (typified by HRAS and MYC) can cooperate to elicit complete transformation. 3132710 1988
Entrez Id: 6294
Gene Symbol: SAFB
SAFB
0.040 AlteredExpression phenotype BEFREE The data suggest that the hap gene product may be a novel ligand-responsive regulatory protein whose inappropriate expression in liver may relate to the hepatocellular carcinogenesis. 2825037 1988
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.030 GeneticVariation phenotype BEFREE These abnormal restriction fragments indicate that in each case a clonal proliferation of cells was present and also suggest that DNA alterations involving the parathyroid hormone locus may be important in the tumorigenesis or clonal evolution of some parathyroid adenomas. 3344017 1988
Entrez Id: 6520
Gene Symbol: SLC3A2
SLC3A2
0.020 GeneticVariation phenotype BEFREE The breakpoint of an inversion of chromosome 14 in a T-cell leukemia: sequences downstream of the immunoglobulin heavy chain locus are implicated in tumorigenesis. 3122210 1988
Entrez Id: 11222
Gene Symbol: MRPL3
MRPL3
0.010 AlteredExpression phenotype BEFREE Therefore, MRL3 overexpression seems to be a property of rapidly dividing cells and is not directly linked to oncogenesis. 2891103 1988