Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
0.400 AlteredExpression phenotype BEFREE In summary, our study determined that miR-203a down-regulation is closely related to tumorigenesis in bladder cancer; thus suggesting that miR-203a is a potential prognostic marker and a potential target in bladder cancer treatment. 30509104 2019
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
0.400 Biomarker phenotype BEFREE The bioinformatics analysis showed that the downstream genes and pathways of miR-203 was closely associated with tumorigenesis. 31411110 2019
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
0.400 AlteredExpression phenotype BEFREE Our data demonstrated that the increased miR-203 level was significantly associated with significant increase in the ability of proliferation, colony and spheres formation, migration, and tumorigenesis in A375 and NA8 cells. 31016725 2019
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
0.400 Biomarker phenotype BEFREE In summary, miR‑203a‑3p may enhance the development and oncogenesis of BC, and IGF1 was defined as a hub gene of miR‑203a‑3p in BC. 30320391 2018
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
0.400 Biomarker phenotype BEFREE MicroRNA-203 Inhibits Long Noncoding RNA HOTAIR and Regulates Tumorigenesis through Epithelial-to-mesenchymal Transition Pathway in Renal Cell Carcinoma. 29440295 2018
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
0.400 AlteredExpression phenotype BEFREE We have demonstrated that attenuated miR-203 expression in APAs increases aldosterone production and the tumorigenesis of adrenal cells by activating the Wnt5a/β-catenin pathway. 30085132 2018
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
0.400 Biomarker phenotype BEFREE Together with the tumor suppressive effect on HCC, miR-203 would be an ideal candidate for promoting liver regeneration in HCC patients undergoing liver resection without the risk of tumorigenesis or cancer recurrence. 28501131 2017
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
0.400 Biomarker phenotype BEFREE Importantly, the increased survival of tumor-bearing mice caused by knockdown of REST in HR-GSCs was reversed by double knockdown of REST and either miR-203 or miR-124, indicating that these 2 miRs are critical tumor suppressors that are repressed in REST-mediated tumorigenesis. 28040710 2017
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
0.400 AlteredExpression phenotype BEFREE We previously showed that miR-203a is expressed at relatively low levels in GBM patients, and ectopic miR-203a expression in GBM cell lines inhibited cell proliferation and migration, increased sensitivity to apoptosis induced by interferon (IFN) or temozolomide <i>in vitro</i>, and inhibited GBM tumorigenesis <i>in vivo</i>. 29348882 2017
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
0.400 Biomarker phenotype BEFREE However, further studies are needed to clarify the role of ΔNp63 and miR-203 in cervical carcinogenesis and, thus, determine how they can be applied in new strategies for diagnosis. 27466497 2016
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
0.400 Biomarker phenotype BEFREE Likewise, restoration of HOXD3 counteracted the effects of miR-203a expression.In conclusion, our findings are the first to demonstrate that EGR1 is a key player in the transcriptional control of miR-203a, and that miR-203a acts as an anti-oncogene to suppress HCC tumorigenesis by targeting HOXD3 through EGFR-related cell signaling pathways. 27244890 2016
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
0.400 AlteredExpression phenotype BEFREE Ectopic miR203 expression in glioblastoma cell lines inhibited cell proliferation and migration, increased sensitivity to apoptosis induced by interferon or temozolomide in vitro, and inhibited tumorigenesis in vivo. 27705947 2016
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
0.400 AlteredExpression phenotype BEFREE Down-regulation of the miR-203 reportedly contributes to oncogenesis and chemo-resistance in multiple cancers. 26847520 2016
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
0.400 AlteredExpression phenotype BEFREE Take together, our results demonstrated that miR-203 act as a tumor suppressor miRNA through regulating RAB22A expression and suggested its involvement in osteosarcoma progression and carcinogenesis. 26382657 2015
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
0.400 Biomarker phenotype BEFREE Our results support the involvement of miR-20a and miR-203 in cervical tumorigenesis. 23725129 2013
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
0.400 Therapeutic phenotype CTD_human Moreover, we identified that miR-203 may suppress the tumorigenesis at least in part through negatively regulating its target gene ABL1. 23968727 2013
Entrez Id: 406986
Gene Symbol: MIR203A
MIR203A
0.400 Biomarker phenotype BEFREE Moreover, we identified that miR-203 may suppress the tumorigenesis at least in part through negatively regulating its target gene ABL1. 23968727 2013