Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
0.170 Biomarker disease BEFREE Targeting circFoxo3/Foxo3/EMT may provide an applicable strategy for exploring potential prognostic and therapeutic approaches for prostate cancer. 31593800 2020
Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
0.170 Biomarker disease BEFREE These results contribute to insights into the metastatic mechanisms of EMT-PCBSLCs in PCa. 31122254 2019
Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
0.170 GeneticVariation disease GWASCAT Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. 29892016 2018
Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
0.170 Biomarker disease BEFREE Here we found that ASC-J9<sup>®</sup> could suppress PCa cell invasion via inducing the sumoylation of STAT3, thereby inhibiting the STAT3 phosphorylation that led to suppress the EMT-SNAIL2 signals in both PCa DU145 and PC3 AR-negative cells. 29425687 2018
Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
0.170 GeneticVariation disease GWASCAT Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21. 27262462 2016
Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
0.170 GeneticVariation disease GWASCAT A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. 26034056 2015
Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
0.170 GeneticVariation disease GWASCAT Two susceptibility loci identified for prostate cancer aggressiveness. 25939597 2015
Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
0.170 AlteredExpression disease BEFREE Aberrant methylation contributes to the reduced expression of OCT3 in prostate cancer. 22231567 2013
Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
0.170 Biomarker disease BEFREE Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis. 22730461 2012
Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
0.170 Biomarker disease BEFREE DU145 and PC3 human prostate cancer cell lines (ATCC), tumor tissue from patients with prostate cancer and normal prostate tissue were evaluated for the reprogramming factors OCT3/4 (Cell Signaling Technology), SOX2, Klf4 (Santa Cruz Biotechnology, Santa Cruz, California), Nanog (BioLegend) and c-Myc (Cell Signaling) by semiquantitative reverse transcriptase-polymerase chain reaction, histological and immunohistochemical analysis. 20303530 2010
Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
0.170 AlteredExpression disease BEFREE The objective of this study was to investigate the transcription and the protein expression of Oct 3/4 isoforms in prostate cancer and benign prostate tissue. 19274762 2009
Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3
0.170 GeneticVariation disease GWASCAT Multiple newly identified loci associated with prostate cancer susceptibility. 18264097 2008