Gene: DRD2 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Biomarker disease CTD_human Addiction-related alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self-administration. 16541082 2007
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Therapeutic disease CTD_human Addiction-related alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self-administration. 16541082 2007
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Therapeutic disease CTD_human Cocaine dependence and d2 receptor availability in the functional subdivisions of the striatum: relationship with cocaine-seeking behavior. 15010698 2004
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Biomarker disease CTD_human Cocaine dependence and d2 receptor availability in the functional subdivisions of the striatum: relationship with cocaine-seeking behavior. 15010698 2004
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Biomarker disease CTD_human D2R DNA transfer into the nucleus accumbens attenuates cocaine self-administration in rats. 18418874 2008
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Therapeutic disease CTD_human D2R DNA transfer into the nucleus accumbens attenuates cocaine self-administration in rats. 18418874 2008
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Biomarker disease CTD_human Dopamine D1- and D2-like receptor mechanisms in relapse to cocaine-seeking behavior: effects of selective antagonists and agonists. 10900248 2000
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Therapeutic disease CTD_human Dopamine D1- and D2-like receptor mechanisms in relapse to cocaine-seeking behavior: effects of selective antagonists and agonists. 10900248 2000
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Therapeutic disease CTD_human Dopamine D3 and D2 receptor mechanisms in the abuse-related behavioral effects of cocaine: studies with preferential antagonists in squirrel monkeys. 20494958 2010
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Biomarker disease CTD_human Dopamine D3 and D2 receptor mechanisms in the abuse-related behavioral effects of cocaine: studies with preferential antagonists in squirrel monkeys. 20494958 2010
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Biomarker disease CTD_human Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats. 15042275 2004
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Therapeutic disease CTD_human Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats. 15042275 2004
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Biomarker disease RGD High and low doses of cocaine intake are differentially regulated by dopamine D2 receptors in the ventral tegmental area and the nucleus accumbens. 29454035 2018
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 GeneticVariation disease BEFREE In this same group, interaction analysis demonstrated that the presence of DRD2-T allele and concomitant absence of DRD4-7R allele were associated with risk for crack cocaine addiction. 30367264 2019
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Therapeutic disease CTD_human Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. 16971900 2006
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Biomarker disease CTD_human Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. 16971900 2006
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 GeneticVariation disease BEFREE Moreover, DRD2 alleles are not associated with severity of cocaine dependence in this sample. 10023512 1999
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Biomarker disease CTD_human Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement. 17332411 2007
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Therapeutic disease CTD_human Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement. 17332411 2007
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 GeneticVariation disease BEFREE Our data do not support a role for the dopamine D2 receptor gene TaqI A and dopamine D3 receptor gene BalI gene polymorphisms in the susceptibility to cocaine dependence in a Brazilian sample. 16094250 2005
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 GeneticVariation disease BEFREE Our study suggests that there is no association between the DRD2 and DAT1 polymorphisms and CD. 20170711 2010
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Biomarker disease CTD_human Relapse to cocaine- and heroin-seeking behavior mediated by dopamine D2 receptors is time-dependent and associated with behavioral sensitization. 11751029 2002
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Therapeutic disease CTD_human Relapse to cocaine- and heroin-seeking behavior mediated by dopamine D2 receptors is time-dependent and associated with behavioral sensitization. 11751029 2002
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Biomarker disease BEFREE Repeat variation in the human PER2 gene as a new genetic marker associated with cocaine addiction and brain dopamine D2 receptor availability. 22832851 2012
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.800 Biomarker disease PSYGENET Repeat variation in the human PER2 gene as a new genetic marker associated with cocaine addiction and brain dopamine D2 receptor availability. 22832851 2012