Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3351
Gene Symbol: HTR1B
HTR1B
0.500 Therapeutic disease CTD_human Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor. 9603521 1998
Entrez Id: 3351
Gene Symbol: HTR1B
HTR1B
0.500 Biomarker disease PSYGENET These findings suggest that targeting 5-HT(1B)Rs may lead to a novel treatment for cocaine dependence and that the therapeutic efficacy of these treatments may vary depending on the stage of the addiction cycle. 22541946 2012
Entrez Id: 3351
Gene Symbol: HTR1B
HTR1B
0.500 Biomarker disease PSYGENET Thus, 5-HT(1B) mRNA is upregulated by repeated exposure to cocaine and perhaps by social stress as well; both of these factors are relevant to the risk for relapse in cocaine addiction. 17059838 2007
Entrez Id: 3351
Gene Symbol: HTR1B
HTR1B
0.500 Therapeutic disease CTD_human 5-HT(1B) receptors in nucleus accumbens efferents enhance both rewarding and aversive effects of cocaine. 17509084 2007
Entrez Id: 3351
Gene Symbol: HTR1B
HTR1B
0.500 Biomarker disease CTD_human Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor. 9603521 1998
Entrez Id: 3351
Gene Symbol: HTR1B
HTR1B
0.500 Biomarker disease CTD_human 5-HT(1B) receptors in nucleus accumbens efferents enhance both rewarding and aversive effects of cocaine. 17509084 2007