Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
0.330 GeneticVariation disease BEFREE Our results provide evidence for strong selection in the nicotinic receptor gene cluster on chromosome 8, previously found to be significantly associated with both nicotine and cocaine dependence, as well as evidence selection acting on the region containing the CHRNA5 nicotinic receptor gene on chromosome 15, that is genome wide significant for risk for nicotine dependence. 26270548 2015
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
0.330 Biomarker disease PSYGENET To investigate the possible contribution of rare variants to the development of substance dependencies other than nicotine dependence, specifically alcohol and cocaine dependence, we undertook pooled sequencing of the coding regions and flanking sequence of CHRNA5, CHRNA3, CHRNB4, CHRNA6 and CHRNB3 in 287 African American and 1028 European American individuals from the Collaborative Study of the Genetics of Alcoholism (COGA). 24057674 2014
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
0.330 GeneticVariation disease BEFREE The strongest association signal in either sample was between rs684513 in CHRNA5 and cocaine dependence (OR=1.43, P=0.0004) in the AA replication set. 20485328 2010
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
0.330 Biomarker disease PSYGENET The strongest association signal in either sample was between rs684513 in CHRNA5 and cocaine dependence (OR=1.43, P=0.0004) in the AA replication set. 20485328 2010
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
0.330 Biomarker disease PSYGENET In the FSCD, there was a significant association between the CHRNA5 variant and cocaine dependence (odds ratio = .67 per allele, p = .0045, assuming an additive genetic model), but in the reverse direction compared with that previously observed for nicotine dependence. 18519132 2008
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
0.330 Biomarker disease PSYGENET We applied this method to correlated SNPs in the cholinergic nicotinic receptor gene cluster CHRNA5-CHRNA3-CHRNB4, in a case-control study of cocaine dependence composed of 504 European-American and 583 African-American samples. 18759969 2008
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
0.330 GeneticVariation disease BEFREE In the FSCD, there was a significant association between the CHRNA5 variant and cocaine dependence (odds ratio = .67 per allele, p = .0045, assuming an additive genetic model), but in the reverse direction compared with that previously observed for nicotine dependence. 18519132 2008