| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | AlteredExpression | disease | BEFREE | The prognostic value of p16 and p53 expression for survival after vulvar cancer: A systematic review and meta-analysis. | 30415992 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | To determine significance of the tumor infiltrating immune cells and p16Ink4a-status for better outcome of patients with vulvar cancer. | 28515351 | 2017 | ||||
|
0.080 | Biomarker | disease | BEFREE | The overexpression of p16 is not a surrogate marker for high-risk human papilloma virus genotypes and predicts clinical outcomes for vulvar cancer. | 27411473 | 2016 | ||||
|
0.080 | Biomarker | disease | BEFREE | The p16INK4a might be associated with a higher survival and indicates better prognosis of vulvar cancer. | 27031618 | 2016 | ||||
|
0.080 | Biomarker | disease | BEFREE | Prognostication of vulvar cancer based on p14ARF status: molecular assessment of transcript and protein. | 22878614 | 2013 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | This study compared the HPV genotype prevalence, HPV-16 variant distribution and p16(INK4a)expression in stored vulvar cancer and high-grade VIN biopsy specimens from women residing in Arnhem Land, with specimens taken from Indigenous and non-Indigenous women in other regions of NT where there is no observed increase in vulvar cancer incidence. | 23158206 | 2013 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | For the first time, we have shown that p14 expression indicates longer disease-specific survival in patients with vulvar carcinoma. | 16891203 | 2006 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | We conclude (1) that p16(INK4a) epigenetic inactivation most likely represents an early event, insufficient for malignant transformation, that may occur in clinically benign lesions such as LS; (2) that lack of pRb was only detected in fewer than one quarter of the carcinomas and could be considered a late secondary event; and (3) that cyclin-D1, which was overexpressed in VC and VIN, could contribute to the malignant transformation in association with p16 hypermethylation. | 12454817 | 2002 |