Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 GeneticVariation disease CLINVAR Two Missense Mutations in the Primary Autosomal Recessive Microcephaly Gene MCPH1 Disrupt the Function of the Highly Conserved N-Terminal BRCT Domain of Microcephalin. 22855649 2012
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR Genetic and histopathologic evaluation of BRCA1 and BRCA2 DNA sequence variants of unknown clinical significance. 16489001 2006
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR A specific GFP expression assay, penetrance estimate, and histological assessment for a putative splice site mutation in BRCA1. 12815598 2003
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR Evaluation of unclassified variants in the breast cancer susceptibility genes BRCA1 and BRCA2 using five methods: results from a population-based study of young breast cancer patients. 18284688 2008
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR BRCA1 germline mutations and tumor characteristics in Chinese women with familial or early-onset breast cancer. 18512148 2009
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR Genetic diagnosis of familial breast cancer using clonal sequencing. 20127978 2010
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR BRCA1-related breast cancer in Austrian breast and ovarian cancer families: specific BRCA1 mutations and pathological characteristics. 9663595 1998
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR Prediction of pathogenic mutations in patients with early-onset breast cancer by family history. 12672316 2003
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR Personalized genomic disease risk of volunteers. 24082139 2013
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR Founder BRCA1 and BRCA2 mutations in French Canadian breast and ovarian cancer families. 9792861 1998
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes. 17924331 2007
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR Description and analysis of genetic variants in French hereditary breast and ovarian cancer families recorded in the UMD-BRCA1/BRCA2 databases. 22144684 2012
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR Comprehensive BRCA1 and BRCA2 mutation analyses and review of French Canadian families with at least three cases of breast cancer. 20694749 2010
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR Spectrum and characterisation of BRCA1 and BRCA2 deleterious mutations in high-risk Czech patients with breast and/or ovarian cancer. 18489799 2008
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR Prostate cancer in male BRCA1 and BRCA2 mutation carriers has a more aggressive phenotype. 18182994 2008
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR Gene panel sequencing in familial breast/ovarian cancer patients identifies multiple novel mutations also in genes others than BRCA1/2. 27616075 2017
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer. 27433846 2016
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR Massively parallel sequencing, aCGH, and RNA-Seq technologies provide a comprehensive molecular diagnosis of Fanconi anemia. 23613520 2013
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 GeneticVariation disease BEFREE Genetic testing for BRCA1/2 mutations associated with hereditary breast and ovarian cancer reveals significant risk information about one's chances of developing cancer. 21797732 2011
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR Efficiency of BRCAPRO and Myriad II mutation probability thresholds versus cancer history criteria alone for BRCA1/2 mutation detection. 19949876 2010
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 Biomarker disease BEFREE The two major susceptibility genes, BRCA1 and BRCA2, are involved in hereditary breast and ovarian cancer syndrome. 20353281 2010
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR Moderate frequency of BRCA1 and BRCA2 germ-line mutations in Scandinavian familial breast cancer. 9150154 1997
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		0.800 CausalMutation disease CLINVAR Comprehensive BRCA1 and BRCA2 mutation analyses and review of French Canadian families with at least three cases of breast cancer. 20694749 2010
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR The prevalence of germ-line TP53 mutations in women diagnosed with breast cancer before age 30. 19714488 2009
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		0.800 CausalMutation disease CLINVAR The contribution of founder mutations to early-onset breast cancer in French-Canadian women. 19863560 2009