Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5077
Gene Symbol: PAX3
PAX3
0.030 AlteredExpression disease BEFREE The results indicate that Pax3 regulates GFAP expression, and that Pax3 may contribute to the evolution of BGSCs towards malignancy. 27432276 2016
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
0.010 AlteredExpression disease BEFREE The results indicate that Pax3 regulates GFAP expression, and that Pax3 may contribute to the evolution of BGSCs towards malignancy. 27432276 2016
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
0.010 Biomarker disease BEFREE Development of a novel imaging agent using peptide-coated gold nanoparticles toward brain glioma stem cell marker CD133. 27721007 2017
Entrez Id: 10215
Gene Symbol: OLIG2
OLIG2
0.010 Biomarker disease BEFREE Here we report that Olig2 expression and DIPG differentiation are mutually exclusive events in vitro, and only DIPG cells that retained Olig2 in vitro formed robust Olig2-positive brainstem glioma with 100% penetrance in a xenograft model. 28339768 2017
Entrez Id: 29126
Gene Symbol: CD274
CD274
0.010 Biomarker disease BEFREE PD-L1 staining was detected in 59.7% of brainstem glioma specimens (37/62). 29137285 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.120 AlteredExpression disease BEFREE Immunofluorescence of p53 was shown activated following BGSCs differentiation. 29937714 2018
Entrez Id: 5077
Gene Symbol: PAX3
PAX3
0.030 Biomarker disease BEFREE Then, the function of PAX3 in BGSCs were sequentially investigated <i>in vitro</i> and <i>in vivo</i>. 29937714 2018
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
0.010 Biomarker disease BEFREE In addition, hypoxia inducible factor-1α (HIF-1α) might be a potential upstream regulator of PAX3 in differentiated BGSCs under hypoxia. 29937714 2018