Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.060 Biomarker phenotype BEFREE IL-2, IL-4, TNF-α, and IFN-γ levels in peripheral blood were significantly increased among the clinical responders (<i>p</i> < 0.05) while IL-6 and IL-10 were elevated among those with progressive disease (<i>p</i> < 0.05). 31795830 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.060 Biomarker phenotype BEFREE Plasma CD73, IL6, and VEGFD were identified as prognostic markers for progressive disease, and IL6 was associated with worse PFS confirming similar observations made in patients treated with other anti-angiogenic agents. 30929823 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.060 Biomarker phenotype BEFREE These data demonstrate that astrocyte-derived IL-6 is a key mediator of progressive disease and support IL-6 blockade as a viable intervention strategy to combat progressive MS. 25896970 2015
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.060 AlteredExpression phenotype BEFREE The only correlation found was an increase in IL-6 gene expression in patients with progressive disease. 23684533 2013
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.060 GeneticVariation phenotype BEFREE Our aims were to assess whether interleukin 6 (IL-6) promoter polymorphisms are associated with chronic hepatitis C virus (HCV) infection and to clarify the role of IL-6 haplotypes in facilitating progressive disease. 21072509 2011
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.060 Biomarker phenotype BEFREE In patients with multiple myeloma OSM is frequently found in the serum and OSM has been associated with serum IL-6 and progressive disease. 11818668 2002