Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
0.030 Biomarker phenotype BEFREE Thus, identifying coactivators that bind to these mutant ERα proteins may offer new therapeutic targets for endocrine-resistant cancer. 29748621 2018
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
0.030 GeneticVariation phenotype BEFREE ESR1 mutations are not associated with clinical resistance to fulvestrant in this study. 27174596 2016
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
0.030 Biomarker phenotype BEFREE These data implicate LBD-mutant forms of ER in mediating clinical resistance to hormonal therapy and suggest that more potent ER antagonists may be of substantial therapeutic benefit. 24185512 2013