Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 GeneticVariation disease BEFREE Also, there was significant association of mutant allele and genotypes of IL-10 [-1082 A>G (rs1800896)] with postmenopausal BC. 22818022 2012
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 GeneticVariation disease BEFREE IL-10 rs1800871 (TC/CC) was associated with a reduced BC risk (OR, 0.74 [95% CI, 0.55-1.00]) but had no interaction with EBV infection on BC risk. 22095765 2012
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 Biomarker disease BEFREE For literature collection, we conducted PubMed search with keywords "IL-10" and "breast cancer". 22057973 2012
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 GeneticVariation disease BEFREE In conclusion, the present meta-analysis suggests a lack of association between the two SNPs (rs1800896 and rs1800872) in the IL-10 gene promoter and breast cancer risk. 20737205 2012
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 GeneticVariation disease BEFREE Our findings suggest that IL-10 promoter polymorphisms participate in the progression of breast cancer rather than in its initial development in Chinese Han women. 20553628 2010
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 PosttranslationalModification disease BEFREE Hypomethylation of the interleukin-10 gene in breast cancer tissues. 20646924 2010
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 GeneticVariation disease BEFREE Our data suggest that the rare allele of IL-10 592C>A may be a potential prognostic marker in breast cancer for disease-free survival. 19437115 2010
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 AlteredExpression disease BEFREE Theses results indicate that T cell response was downregulated by interleukin-10 overexpression in sentinel lymph node with breast cancer. 17762971 2007
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 GeneticVariation disease BEFREE Our data suggest that IL-10 (-1082, -819, -592) GCC/ATA haplotype and IL-6-174 GC genotype seem to be potential risk factors for the development of breast cancer. 17965799 2007
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 GeneticVariation disease BEFREE The aim of this study was to evaluate any role of specific SNPs in the interleukin genes IL1A, IL1B, IL1RN, IL4R, IL6 and IL10 in predisposition to breast cancer susceptibility and severity. 16842617 2006
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 GeneticVariation disease BEFREE Therefore we conclude that the IL-10 -592C > A promoter polymorphism may be associated with a reduced breast cancer risk. 15803357 2005
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 Biomarker disease BEFREE The other cytokine genotypes studied (IL-10, IL-6, IFN-gamma, and TNF-alpha production were not associated with breast cancer overall or relapse status. 15945506 2005
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.400 GeneticVariation disease BEFREE The effects of interleukin 10 and interferon gamma cytokine gene polymorphisms on survival after autologous bone marrow transplantation for patients with breast cancer. 15931634 2005