×
Entrez Id:
407021
Gene Symbol:
MIR29A
MIR29A
0.400
AlteredExpression
disease
BEFREE
In this study, we found that miR-29a was up-regulated in BCSCs, in aggressive breast cancer cell line and in breast cancer tissues.
30792382
2019
×
Entrez Id:
407021
Gene Symbol:
MIR29A
MIR29A
0.400
AlteredExpression
disease
BEFREE
This miR-29a was found to be indeed overexpressed in a substantial number of Breast cancer patient samples and cell lines as well, suggesting one of the key mechanisms of PC4 downregulation.
31839879
2019
×
Entrez Id:
407021
Gene Symbol:
MIR29A
MIR29A
0.400
AlteredExpression
disease
BEFREE
Tamoxifen differentially regulates miR-29b-1 and miR-29a expression depending on endocrine-sensitivity in breast cancer cells.
27986463
2017
×
Entrez Id:
407021
Gene Symbol:
MIR29A
MIR29A
0.400
Biomarker
disease
BEFREE
These results have provided us with information regarding the molecular mechanisms by which hyperinsulinemia promotes breast cancer occurrence and development and thus leads to a poor prognosis in breast cancer patients and indicate that miR-29a plays an important role in breast cancer development and invasion.
28427228
2017
×
Entrez Id:
407021
Gene Symbol:
MIR29A
MIR29A
0.400
AlteredExpression
disease
BEFREE
Taken together, our results suggest that miR-29a is an important regulator of tumor necrosis factor receptor 1 expression in breast cancer and functions as a tumor suppressor by targeting tumor necrosis factor receptor 1 to influence the growth of MCF-7 cell.
28222663
2017
×
Entrez Id:
407021
Gene Symbol:
MIR29A
MIR29A
0.400
AlteredExpression
disease
BEFREE
Increased levels of microRNA-29a in the serum of breast cancer patients have been reported.
26802653
2016
×
Entrez Id:
407021
Gene Symbol:
MIR29A
MIR29A
0.400
Biomarker
disease
BEFREE
Thus, miR-29a may be a potential target for the patients who acquired ADR-resistance during the treatment of breast cancer .
27523474
2016
×
Entrez Id:
407021
Gene Symbol:
MIR29A
MIR29A
0.400
Biomarker
disease
BEFREE
However, as a tumor promoter, miR-29 mediates epithelial-mesenchymal transition (EMT) and promotes metastasis in breast cancer and colon cancer.
24573597
2014
×
Entrez Id:
407021
Gene Symbol:
MIR29A
MIR29A
0.400
Biomarker
disease
BEFREE
microRNA-29 negatively regulates EMT regulator N-myc interactor in breast cancer .
25174825
2014
×
Entrez Id:
407021
Gene Symbol:
MIR29A
MIR29A
0.400
Biomarker
disease
BEFREE
Taken together, our data suggests Mir-29a plays an important role in inhibiting growth of breast cancer cells and arresting cells at G0/G1 phase.
24289849
2013
×
Entrez Id:
407021
Gene Symbol:
MIR29A
MIR29A
0.400
Biomarker
disease
BEFREE
MiR-222 and miR-29a contribute to the drug-resistance of breast cancer cells.
23994196
2013
×
Entrez Id:
407021
Gene Symbol:
MIR29A
MIR29A
0.400
Biomarker
disease
CTD_human
Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin.
20099276
2010
×
Entrez Id:
407021
Gene Symbol:
MIR29A
MIR29A
0.400
AlteredExpression
disease
BEFREE
We also observed enhanced miR-29a and reduced TTP levels in breast cancer patient samples, indicating relevance for human disease.
19247375
2009