| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.700 | Biomarker | disease | CTD_human | In the current study, next-generation sequencing (NGS) and Sanger Sequencing (SGS) was used for the mutational analysis of PIK3CA in 186 breast carcinomas. | 26587011 | 2015 | ||||
|
0.700 | Biomarker | disease | CTD_human | Molecular profiling of single circulating tumor cells with diagnostic intention. | 25358515 | 2014 | ||||
|
0.700 | Biomarker | disease | CTD_human | Genomic high-resolution profiling of single CKpos/CD45neg flow-sorting purified circulating tumor cells from patients with metastatic breast cancer. | 25267515 | 2014 | ||||
|
0.700 | Biomarker | disease | CTD_human | In this study, we report the development of a knock-in mouse model for breast cancer where the endogenous Pik3ca allele was modified to allow tissue-specific conditional expression of a frequently found Pik3ca(H1047R) (Pik3ca(e20H1047R)) mutant allele. | 22370636 | 2013 | ||||
|
0.700 | Biomarker | disease | CTD_human | Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. | 21633166 | 2011 | ||||
|
0.700 | Biomarker | disease | CTD_human | In univariate analysis, PI3K pathway aberrations were associated with death from breast cancer; however, this relationship was not maintained in multivariate analysis. | 19685490 | 2010 | ||||
|
0.700 | Biomarker | disease | CTD_human | These findings could have important implications for the treatment of PIK3CA-mutant BCs and the development of PI3K/mTOR inhibitors. | 20479250 | 2010 | ||||
|
0.700 | Biomarker | disease | CTD_human | Knockin of mutant PIK3CA activates multiple oncogenic pathways. | 19196980 | 2009 | ||||
|
0.700 | CausalMutation | disease | CGI |