This study aims to explore relationships between <sup>1</sup>H-NMR spectroscopy derived plasma metabolite concentrations and the uptake of labeled glucose (<sup>18</sup>F-FDG) in lung cancer tissue.
31P-NMR spectra were obtained from the perchloric acid extracts of normal lung and lung cancer tissues obtained at surgery, and from extracts of neoplastic cells cultured in vitro.
This study indicates that the <sup>1</sup>H-NMR-derived relative plasma concentration of glutamate allows discrimination between lung cancer and lung inflammation.