Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 253260
Gene Symbol: RICTOR
RICTOR
0.330 GenomicAlterations disease CGI
Entrez Id: 4916
Gene Symbol: NTRK3
NTRK3
0.310 GeneticVariation disease UNIPROT
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
0.310 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 283106
Gene Symbol: CSNK2A3
CSNK2A3
0.310 GeneticVariation disease UNIPROT
Entrez Id: 5885
Gene Symbol: RAD21
RAD21
0.310 CausalMutation disease CGI
Entrez Id: 6016
Gene Symbol: RIT1
RIT1
0.300 CausalMutation disease CGI
Entrez Id: 894
Gene Symbol: CCND2
CCND2
0.300 GenomicAlterations disease CGI
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
0.200 GeneticVariation disease CLINVAR
Entrez Id: 5519
Gene Symbol: PPP2R1B
PPP2R1B
0.100 CausalMutation disease CLINVAR
Entrez Id: 127262
Gene Symbol: TPRG1L
TPRG1L
0.010 Biomarker disease BEFREE "MOVER" method was used to analyze the interaction between smoking prevalence and PM2.5 pollution in relation to lung cancer mortality. 29913439 2018
Entrez Id: 9817
Gene Symbol: KEAP1
KEAP1
0.100 Biomarker disease BEFREE "Keaping" a lid on lung cancer: the Keap1-Nrf2 pathway. 30009666 2018
Entrez Id: 100505887
Gene Symbol: LINC01672
LINC01672
0.040 GeneticVariation disease BEFREE <b>Abbreviation used:</b> A549 (human lung carcinoma), Caco-2 (Human ColonCarcinoma), CHCl3 (Chloroform), HCT 116 (Human Colon Carcinoma), HepG2 (Liver Hepatocellular Carcinoma), HT-29 (Human Colorectal Adenocarcinoma), MCF-7 (Michigan Cancer Foundation-7; Human Breast Adenocarcinoma), MeOH (Methanol), NMR Nuclear Magnetic Resonance), PBS (Phosphate Buffered Saline), PC-3 (Human Prostate Cancer), PTLC (Preparative Thin Layer Chromatography), RPMI-1640 (Roswell Park Memorial Institute medium), TLC (ThinLayer Chromatography). 28479724 2017
Entrez Id: 29126
Gene Symbol: CD274
CD274
0.100 Biomarker disease BEFREE <b>Background:</b> Predictive biomarkers for immunotherapy in lung cancer are intensively investigated; however, correlations between PD-L1/PD-1 expressions and clinical features or histopathological tumor characteristics determined on hematoxylin and eosin stained sections have not extensively been studied. 31002007 2019
Entrez Id: 89870
Gene Symbol: TRIM15
TRIM15
0.010 Biomarker disease BEFREE <b>Conclusion</b>: TRIM15 could act as a diagnostic predictor or therapeutic target for lung cancer treatments. 30854090 2019
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
0.070 Biomarker disease BEFREE <b>Conclusion</b>: Our results verified that NRP1, inflammatory factors, chemokines and related signaling pathways, which affect the transformation of related cell components and thus lung cancer cell immune tolerance and migratory ability, all play an important role in radiation resistance. 31417646 2019
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
0.100 Biomarker disease BEFREE <b>Conclusion</b>: Taken together, our data confirms that GLUT1 promotes the malignant phenotype of NSCLC through integrin β1/Src/FAK signaling, which provides a new therapeutic target for the treatment and research of lung cancer. 31598171 2019
Entrez Id: 3688
Gene Symbol: ITGB1
ITGB1
0.050 Biomarker disease BEFREE <b>Conclusion</b>: Taken together, our data confirms that GLUT1 promotes the malignant phenotype of NSCLC through integrin β1/Src/FAK signaling, which provides a new therapeutic target for the treatment and research of lung cancer. 31598171 2019
Entrez Id: 1045
Gene Symbol: CDX2
CDX2
0.040 GeneticVariation disease BEFREE <b>Conclusion</b>: The results of this meta-analysis suggested that Bsm1, Taq1 and Cdx-2 polymorphism may contribute to lung cancer susceptibility, more studies need be conducted to confirm in the future. 31333781 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.100 Biomarker disease BEFREE <b>Conclusion:</b> p16 play an unique role in lung cancer survival. 31157548 2019
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
0.100 Biomarker disease BEFREE <b>Conclusion:</b> p16 play an unique role in lung cancer survival. 31157548 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.100 Biomarker disease BEFREE <b>Conclusion:</b> CRP may be a prediagnostic marker for lung cancer, and when present with other symptoms could facilitate the investigation of high-risk individuals. 31668096 2019
Entrez Id: 260431
Gene Symbol: COPD
COPD
0.100 Biomarker disease BEFREE <b>Conclusion:</b> NSCLC patients with preexisting COPD had shorter survival with marked differences in early stages of lung cancer. 31118599 2019
Entrez Id: 26230
Gene Symbol: TIAM2
TIAM2
0.010 Biomarker disease BEFREE <b>Conclusion:</b> Our results suggest that fibroblast TIAM2 promotes the invasion and migration of lung cancer cell, and OPG might be one of the main cytokines contributing to this pro-cancer process. 31205545 2019
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B
0.020 Biomarker disease BEFREE <b>Conclusion:</b> Our results suggest that fibroblast TIAM2 promotes the invasion and migration of lung cancer cell, and OPG might be one of the main cytokines contributing to this pro-cancer process. 31205545 2019
Entrez Id: 501
Gene Symbol: ALDH7A1
ALDH7A1
0.020 Biomarker disease BEFREE <b>Conclusion:</b> The synergistic effect of PDE inhibitors with platinum-based agents has been demonstrated in lung cancer. 29151951 2017