Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
0.100 Biomarker disease BEFREE <sup>18</sup>F-FDG PET/CT versus CT/MR imaging for detection of neck lymph node metastasis in palpably node-negative oral cavity cancer. 31606761 2020
Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1
0.100 Biomarker disease BEFREE In this study we evaluated the diagnostic accuracy of <sup>68</sup>Ga prostate specific membrane antigen positron emission tomography/computerized tomography for detecting lymph node metastasis in patients with intermediate-high risk prostate cancer. 31487220 2020
Entrez Id: 5979
Gene Symbol: RET
RET
0.100 AlteredExpression disease BEFREE Presence of RET/PTC rearrangement significantly correlated with gender, elevated TSH levels and lymph node metastasis. 30467698 2020
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
0.100 AlteredExpression disease BEFREE Negative P16 expression was significantly associated with NSCLC with lymph node metastasis (p=0.025). 31662516 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.100 Biomarker disease BEFREE The parameters were compared using the Mann-Whitney U-test between the luminal A and luminal B groups, the human epidermal growth factor receptor-2 (HER2)-positive luminal B and HER2-negative luminal B groups, and the lymph node metastasis (LNM)-positive and LNM-negative groups. 31151899 2020
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
0.100 Biomarker disease BEFREE According to this SR, MMP-1, -2, -3, -7, -9, and MT1-MMP seem to play an important role in lymph node metastasis of OSCC. 31750584 2020
Entrez Id: 3956
Gene Symbol: LGALS1
LGALS1
0.100 AlteredExpression disease BEFREE The expression of Galectin-1 in endometrial adenocarcinoma was significantly different among tissues of different histological grades, pathological stages, degrees of myometrial infiltration, or lymph node metastasis (p > 0.05). 31487707 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.100 Biomarker disease BEFREE We considered that the group without the addition of taxane might be present in patients with ER-positive, HER2-negative lymph node metastases. 31327134 2020
Entrez Id: 6275
Gene Symbol: S100A4
S100A4
0.100 AlteredExpression disease BEFREE Mts1 was highly expressed in patients with thyroid cancer and high Mts1 levels were related to poor prognoses such as lymph node metastasis. 31467231 2020
Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1
0.100 Biomarker disease BEFREE Use of gallium-68 prostate-specific membrane antigen positron-emission tomography for detecting lymph node metastases in primary and recurrent prostate cancer and location of recurrence after radical prostatectomy: an overview of the current literature. 31680398 2020
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
0.100 Biomarker disease BEFREE The purpose of this study was to investigate if FDG uptake metrics in primary tumor and lymph node metastases in patients with oropharyngeal squamous cell carcinoma (OPSCC) has a prognostic value beyond UICC8 staging in a multiple endpoint model. 31720757 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.100 Biomarker disease BEFREE In the multivariate analysis, negative p16 immunostaining was associated with a worse overall survival together with advanced FIGO stage and lymph node metastases. 31492932 2020
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
0.100 Biomarker disease BEFREE When MMR proteins were studied separately, MLH1/PMS2 loss was related to deep myometrial invasion (p=0.019 and p=0.036, respectively) and MSH6 loss to lymph-node metastases (p=0.04). 31786870 2020
Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1
0.100 Biomarker disease BEFREE To assess the performance of [<sup>68</sup>Ga] Ga-prostate-specific membrane antigen conjugate 11 positron emission tomography (PSMA-PET) in detecting PCa lymph node metastasis using pathologic confirmation through sLND. 31147628 2020
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.100 Biomarker disease BEFREE BRCA1 carriers frequently experienced lung and distant lymph node metastasis, whereas BRCA2 carriers and noncarriers most often experienced bone metastasis. 31581314 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.100 AlteredExpression disease BEFREE Mts1 was highly expressed in patients with thyroid cancer and high Mts1 levels were related to poor prognoses such as lymph node metastasis. 31467231 2020
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
0.100 AlteredExpression disease BEFREE Lymph node metastases had significantly higher expression levels of CD24 (P = 0.01) and CD133 (P < 0.05) than primary tumors. 31811857 2020
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
0.100 Biomarker disease BEFREE According to this SR, MMP-1, -2, -3, -7, -9, and MT1-MMP seem to play an important role in lymph node metastasis of OSCC. 31750584 2020
Entrez Id: 9076
Gene Symbol: CLDN1
CLDN1
0.100 Biomarker disease BEFREE Although the expression level of claudin-1 based on immunohistochemistry was not associated with TSCC progression, within the high claudin-1 expression group, the incidence of the intracellular localization of claudin-1 was correlated with cervical lymph node metastasis. 31769164 2020
Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1
0.100 GeneticVariation disease BEFREE The aim of this study was to assess the added value of <sup>68</sup>Ga-PSMA-11 PET in predicting lymph node metastasis in men with intermediate- or high-risk prostate cancer. 31522272 2020
Entrez Id: 354
Gene Symbol: KLK3
KLK3
0.100 Biomarker disease BEFREE The aim of this study was to determine the prognostic significance of ERG and KPNA2 expression, and their association to early prostate-specific antigen (PSA) biochemical recurrence in advanced PC with lymph node metastases. 31809312 2020
Entrez Id: 7424
Gene Symbol: VEGFC
VEGFC
0.100 Biomarker disease BEFREE Vascular endothelial growth factor C (VEGF-C) has been reported to be responsible for the lymphatic vessel density, tumor staging and lymph node metastasis, resulting in the failure of nasopharyngeal carcinoma (NPC) after radiotherapy. 31478229 2020
Entrez Id: 5979
Gene Symbol: RET
RET
0.100 GeneticVariation disease BEFREE The univariate analysis showed that age (P = .008), gender (P = .016), smoking history (P = .010), lymph node metastasis (P = .003), and three driver genes, positive epidermal growth factor receptor (EGFR) mutation (P = .001), positive anaplastic lymphoma kinase (ALK) gene fusion (P = .021), and positive rearranged during transfection (RET) gene fusion (P = .003), were the factors influencing the incidence of brain metastasis. 31769228 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 GeneticVariation disease BEFREE The univariate analysis showed that age (P = .008), gender (P = .016), smoking history (P = .010), lymph node metastasis (P = .003), and three driver genes, positive epidermal growth factor receptor (EGFR) mutation (P = .001), positive anaplastic lymphoma kinase (ALK) gene fusion (P = .021), and positive rearranged during transfection (RET) gene fusion (P = .003), were the factors influencing the incidence of brain metastasis. 31769228 2020
Entrez Id: 1366
Gene Symbol: CLDN7
CLDN7
0.100 Biomarker disease BEFREE Although the expression level of claudin-1 based on immunohistochemistry was not associated with TSCC progression, within the high claudin-1 expression group, the incidence of the intracellular localization of claudin-1 was correlated with cervical lymph node metastasis. 31769164 2020