Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | AlteredExpression | disease | BEFREE | In addition, we found that the expression of LYN, an Src family tyrosine kinase, was inversely correlated with miR-122-5p expression in GC tissues by using western blot analysis, immunohistochemistry, and qRT-PCR assays. | 31828293 | 2020 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Also, suppression of miR‑122‑5p significantly reduced AFP levels and proliferation in AFPGC through an induction of apoptosis. | 30816512 | 2019 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | The results demonstrated that miR-122 expression was reduced in cisplatin-resistant gastric cancer. | 31152437 | 2019 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Plasma <i>miR-122-5p</i> expression levels were also significantly higher in the AFPGC patients than the health volunteers and the non-AFPGC patients (<i>P</i> < 0.05) and were strongly correlated with plasma AFP levels (<i>r</i> = 0.7975, <i>P</i> < 0.0001). | 30364858 | 2018 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | The expression of miR-122-5p in GC tissues and cells was significantly down-regulated, whereas DUSP4 expression was up-regulated. | 29509059 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | All these findings suggest that miR-122-5p may be involved in progression of GC and could be a new therapeutic target for this disease. | 29442023 | 2017 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | In addition, cAMP responsive element binding protein 1 (CREB1) was identified as a direct target of miR-122, and its expression was negatively correlated with miR-122 expression in GC tissues (<i>r</i> = -0.711, <i>P</i> < 0.001). | 28337380 | 2017 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Our results demonstrated that assessment of decreased circulating miR-122 and elevated circulating miR-192 levels has the potential to improve early detection of DM in GC. | 24481716 | 2014 |