Gene: RET ×
Source: BEFREE ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5979
Gene Symbol: RET
RET 		0.100 AlteredExpression disease BEFREE We demonstrate that ETV5 is regulated both at the protein and mRNA levels upon ALK activation or inhibition in neuroblastoma cell lines and that this regulation precedes RET modulation. 29321660 2018
Entrez Id: 5979
Gene Symbol: RET
RET 		0.100 AlteredExpression disease BEFREE Specific expression of the ret proto-oncogene in human neuroblastoma cell lines. 2216455 1990
Entrez Id: 5979
Gene Symbol: RET
RET 		0.100 AlteredExpression disease BEFREE Possibly, expression of RET in neuroblastoma merely reflects the differentiation status of the tumor cells. 8786083 1996
Entrez Id: 5979
Gene Symbol: RET
RET 		0.100 AlteredExpression disease BEFREE Transfection of neuroblastoma cell lines with NXF-ARNT2 or SIM2-ARNT2 increased and decreased expression of RET, respectively. 20977903 2011
Entrez Id: 5979
Gene Symbol: RET
RET 		0.100 AlteredExpression disease BEFREE RET gene expression is also involved in Neuroblastoma. 22429913 2012
Entrez Id: 5979
Gene Symbol: RET
RET 		0.100 AlteredExpression disease BEFREE RET expression is enhanced in vitro by several differentiating agents, including retinoic acid (RA), which up-regulates RET expression in neuroblastoma cell lines. 9426223 1997
Entrez Id: 5979
Gene Symbol: RET
RET 		0.100 AlteredExpression disease BEFREE We developed a RET mini-gene reporter system, and showed that MCS+9.7 enhanced HOXB5 trans-activation from RET promoter in human neuroblastoma SK-N-SH cells and in chick embryos. 24794774 2014
Entrez Id: 5979
Gene Symbol: RET
RET 		0.100 AlteredExpression disease BEFREE Quantitative phosphoproteomic analysis identifies activation of the RET and IGF-1R/IR signaling pathways in neuroblastoma. 24349301 2013
Entrez Id: 5979
Gene Symbol: RET
RET 		0.100 AlteredExpression disease BEFREE Chromatin and DNA methylation dynamics during retinoic acid-induced RET gene transcriptional activation in neuroblastoma cells. 20952403 2011
Entrez Id: 5979
Gene Symbol: RET
RET 		0.100 AlteredExpression disease BEFREE We have also demonstrated by the in vitro premethylation of a RET promoter-chloramphenicol acetyltransferase (CAT) gene construct and transient transfection experiments into neuroblastoma cells that the transcriptional activity of the RET promoter is decreased by HpaII (5'-CCGG-3') methylation and abolished by SssI (5'-CG-3') methylation. 9840920 1998