Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 841
Gene Symbol: CASP8
CASP8
0.020 AlteredExpression disease BEFREE The NLRP3/caspase-8 inflammasome pathway is activated in PPMS, possibly as a consequence of hyperuricemia. 29780394 2018
Entrez Id: 841
Gene Symbol: CASP8
CASP8
0.020 Biomarker disease BEFREE Importantly, RIP3-knockout mice exhibited the decrease of FAS-associated protein with a death domain (FADD), cleaved Caspase-8/-3 and Poly (ADP-ribose) polymerase (PARP) in renal samples, along with TUNEL reduction in mice with hyperuricemia. 29518608 2018