Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.560 | CausalMutation | disease | CGI | |||||||
|
0.560 | GenomicAlterations | disease | CGI | |||||||
|
0.560 | GeneticVariation | disease | BEFREE | BAP1 mutations may drive tumor development in a subset of patients with inherited renal cell cancer. | 23709298 | 2013 | ||||
|
0.560 | GeneticVariation | disease | BEFREE | Thus, the combination of gender and mutation of a specific gene, such as BAP1, may have implications not only for prognosis but also for understanding the role of chromatin remodeling gene mutations in kidney cancer progression. | 26484545 | 2015 | ||||
|
0.560 | GeneticVariation | disease | BEFREE | Somatic mutations of BRCA1 associated protein-1 (BAP1) gene were recently found in MM as well as in uveal melanoma and kidney cancer among the Caucasian and Japanese people. | 26246155 | 2015 | ||||
|
0.560 | GeneticVariation | disease | BEFREE | We found a bidirectional association of pleural MM with kidney cancer for overall and for <1 year follow-up, suggesting the involvement of germline BAP1 mutations and increased medical surveillance, while the bidirectional association of pleural MM with unknown primary cancer suggests shared genetic or environmental risk factors. | 27260871 | 2016 | ||||
|
0.560 | Biomarker | disease | CTD_human | Germline BAP1 Mutational Landscape of Asbestos-Exposed Malignant Mesothelioma Patients with Family History of Cancer. | 26719535 | 2016 | ||||
|
0.560 | GeneticVariation | disease | BEFREE | The <i>BAP1</i> gene is mutated in about 10% of patients with ccRCC, the most common form of renal cancer, suggesting that BAP1 is a tumor suppressor. | 30992312 | 2019 | ||||
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0.560 | GeneticVariation | disease | BEFREE | Although we did find three VUS's in BAP1 in three families and a pathogenic variant in MITF in one family, pathogenic germline variants in BAP1, MITF or CDKN2B are not frequent causes of hereditary renal cancer in Denmark. | 31034483 | 2019 |