Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
0.030 AlteredExpression disease BEFREE Oppositely, in specific subsets of renal cancer, NRF2 is constitutively activated and contributes to tumor burden and overall poor prognosis; therefore, there has been a recent interest in studies investigating the benefits of NRF2 inhibition. 31372933 2020
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
0.030 GeneticVariation disease BEFREE Nrf2 gene mutation and single nucleotide polymorphism rs6721961 of the Nrf2 promoter region in renal cell cancer. 31752777 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
0.030 Biomarker disease BEFREE Keap1/Nrf2 pathway in kidney cancer: frequent methylation of KEAP1 gene promoter in clear renal cell carcinoma. 28061437 2017