| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | disease | BEFREE | Germline TP53 mutation spectrum in Sudanese premenopausal breast cancer patients: correlations with reproductive factors. | 30796655 | 2019 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Further studies in larger samples of BC patients of different ages and regions of the country are necessary to provide more definitive TP53 p.Arg337His carrier frequencies in different scenarios. | 30596752 | 2018 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Accordingly, the aim of this study was to assess the spectrum of polymorphisms in TP53 and its negative regulatory gene, MDM2 (SNP309:T>G) in patients with premenopausal breast cancer. | 27957778 | 2017 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Association of rs1219648 in FGFR2 and rs1042522 in TP53 with premenopausal breast cancer in an Iranian Azeri population. | 25292094 | 2014 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The results indicate protective associations of p53 Arg72Pro heterozygous variant with postmenopausal and MDM-2 SNP309G along with p53 Arg72Pro heterozygous variant with premenopausal breast cancer risk. | 17719241 | 2008 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Our data were consistent with increased likelihood of tumors with p53 mutations for premenopausal breast cancer with increased alcohol intake 10 or 20 years previous; for intake of 16 or more drinks per month in the period 20 years before the interview compared with non-drinkers, the OR was 5.25, 95% CI 1.48-18.58. | 14742318 | 2004 | ||||
|
0.080 | Biomarker | disease | BEFREE | We investigated p53 accumulation in tumour specimens from premenopausal breast cancer patients who were randomised to adjuvant chemotherapy (CMF) or postoperative radiotherapy. | 7576743 | 1995 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Four affected members of the family with sarcoma or premenopausal breast cancer showed increased expression of p53 protein in their normal tissues as detected by immunohistochemistry. | 7981072 | 1994 |