Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.320 Biomarker disease BEFREE Berger, Lack of the DNA repair protein O(6)-methylguanine-DNA methyltransferase in histologically normal brain adjacent to primary brain tumors, Proc.Natl.Acad.Sci.U.S.A. 93 (1996) 6941-6946]. 17500046 2007
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.320 Biomarker disease CTD_human MGMT activity, promoter methylation and immunohistochemistry of pretreatment and recurrent malignant gliomas: a comparative study on astrocytoma and glioblastoma. 20131314 2010
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.320 GeneticVariation disease BEFREE The frequencies of MGMT genotypes in examined primary brain tumors were not different from normal subjects. 14669534 2003
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		0.310 Biomarker disease CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819 2017
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		0.310 Biomarker disease CTD_human Naringenin, a flavanone inhibits the proliferation of cerebrally implanted C6 glioma cells in rats. 20932960 2011
Entrez Id: 6657
Gene Symbol: SOX2
SOX2 		0.310 Biomarker disease CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819 2017
Entrez Id: 6657
Gene Symbol: SOX2
SOX2 		0.310 Biomarker disease BEFREE We undertook this study to understand how the transcription factor Sox2 contributes to the malignant phenotype of glioblastoma multiforme (GBM), the most aggressive primary brain tumor. 22069467 2011
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		0.310 GeneticVariation disease BEFREE Cyclin D1 gene G870A variants and primary brain tumors. 23991960 2013
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.310 GeneticVariation disease BEFREE The frequency of CC genotype for CDKN2 p16 540 C>G was significantly two-fold higher (p<0.001) and possessing a C allele conferred a ~7-fold increased risk (p=0.005) of primary brain tumor. 26124340 2015
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.310 Biomarker disease CTD_human Evaluation of genetic alterations in cancer-related genes in lung and brain tumors from B6C3F1 mice exposed to 1,3-butadiene or chloroprene. 16860786 2007
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.310 Biomarker disease CTD_human [p16 protein expression in the transplacental induced brain tumor in rat]. 15144691 2004
Entrez Id: 6285
Gene Symbol: S100B
S100B 		0.300 Biomarker disease CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819 2017
Entrez Id: 5111
Gene Symbol: PCNA
PCNA 		0.300 Biomarker disease CTD_human Naringenin, a flavanone inhibits the proliferation of cerebrally implanted C6 glioma cells in rats. 20932960 2011
Entrez Id: 1559
Gene Symbol: CYP2C9
CYP2C9 		0.300 Biomarker disease CTD_human CYP2C9 polymorphisms in human tumors. 16475710 2006
Entrez Id: 27436
Gene Symbol: EML4
EML4 		0.300 Biomarker disease CTD_human Isolated central nervous system progression on Crizotinib: an Achilles heel of non-small cell lung cancer with EML4-ALK translocation? 22986231 2012
Entrez Id: 5970
Gene Symbol: RELA
RELA 		0.300 Biomarker disease CTD_human Naringenin, a flavanone inhibits the proliferation of cerebrally implanted C6 glioma cells in rats. 20932960 2011
Entrez Id: 3558
Gene Symbol: IL2
IL2 		0.300 Biomarker disease CTD_human Cytokinetic basis for the impaired activation of lymphocytes from patients with primary intracranial tumors. 6319491 1984
Entrez Id: 5444
Gene Symbol: PON1
PON1 		0.300 Biomarker disease CTD_human Risk of brain tumors in children and susceptibility to organophosphorus insecticides: the potential role of paraoxonase (PON1). 16002382 2005
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2 		0.300 Biomarker disease CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819 2017
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		0.300 Biomarker disease CTD_human Resveratrol Targeting of Carcinogen-Induced Brain Endothelial Cell Inflammation Biomarkers MMP-9 and COX-2 is Sirt1-Independent. 22523472 2012
Entrez Id: 10413
Gene Symbol: YAP1
YAP1 		0.300 Biomarker disease CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819 2017
Entrez Id: 7052
Gene Symbol: TGM2
TGM2 		0.300 Therapeutic disease CTD_human Tissue transglutaminase 2 inhibition promotes cell death and chemosensitivity in glioblastomas. 16170020 2005
Entrez Id: 10788
Gene Symbol: IQGAP2
IQGAP2 		0.300 Biomarker disease CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819 2017
Entrez Id: 238
Gene Symbol: ALK
ALK 		0.300 Biomarker disease CTD_human Isolated central nervous system progression on Crizotinib: an Achilles heel of non-small cell lung cancer with EML4-ALK translocation? 22986231 2012
Entrez Id: 1612
Gene Symbol: DAPK1
DAPK1 		0.300 Biomarker disease CTD_human DAPK1 promoter hypermethylaiton in brain metastases and peripheral blood. 17319784 2007