Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6904
Gene Symbol: TBCD
TBCD 		0.300 Biomarker phenotype CTD_human Biallelic Mutations in TBCD, Encoding the Tubulin Folding Cofactor D, Perturb Microtubule Dynamics and Cause Early-Onset Encephalopathy. 27666370 2016
Entrez Id: 1191
Gene Symbol: CLU
CLU 		0.300 Biomarker phenotype CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 5443
Gene Symbol: POMC
POMC 		0.300 Biomarker phenotype CTD_human [A case of Aicardi syndrome with moderate psychomotor retardation]. 2169275 1990
Entrez Id: 5020
Gene Symbol: OXT
OXT 		0.300 Biomarker phenotype CTD_human Oxytocin infusion: acute hyponatraemia, seizures and coma. 19397503 2009
Entrez Id: 6854
Gene Symbol: SYN2
SYN2 		0.300 Biomarker phenotype CTD_human Genetic deletion of synapsin II reduces neuropathic pain due to reduced glutamate but increased GABA in the spinal cord dorsal horn. 18701217 2008
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.300 Biomarker phenotype CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040 2005
Entrez Id: 7249
Gene Symbol: TSC2
TSC2 		0.300 Biomarker phenotype CTD_human Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex. 21062901 2011
Entrez Id: 4852
Gene Symbol: NPY
NPY 		0.300 Biomarker phenotype CTD_human Differential effects of vigabatrin and zonisamide on the neuropeptide Y system in the hippocampus of seizure prone gerbil. 16194568 2005
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.300 Biomarker phenotype CTD_human Pilocarpine-induced status epilepticus increases cell proliferation in the dentate gyrus of adult rats via a 5-HT1A receptor-dependent mechanism. 12646302 2003
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1 		0.300 Biomarker phenotype CTD_human Mutational analysis of GLUT1 (SLC2A1) in Glut-1 deficiency syndrome. 10980529 2000
Entrez Id: 6750
Gene Symbol: SST
SST 		0.300 Biomarker phenotype CTD_human Hippocampal sst(1) receptors are autoreceptors and do not affect seizures in rats. 20134357 2010
Entrez Id: 210
Gene Symbol: ALAD
ALAD 		0.300 Biomarker phenotype CTD_human Lipoic acid alters delta-aminolevulinic dehydratase, glutathione peroxidase and Na+,K+-ATPase activities and glutathione-reduced levels in rat hippocampus after pilocarpine-induced seizures. 19798568 2010
Entrez Id: 6750
Gene Symbol: SST
SST 		0.300 Biomarker phenotype CTD_human [Effect of intracerebral injections of somatostatin and neurotensin on motor functions in seizure]. 7913897 1994
Entrez Id: 5428
Gene Symbol: POLG
POLG 		0.300 Biomarker phenotype CTD_human POLG DNA testing as an emerging standard of care before instituting valproic acid therapy for pediatric seizure disorders. 20138553 2010
Entrez Id: 348980
Gene Symbol: HCN1
HCN1 		0.300 Biomarker phenotype CTD_human Increased seizure severity and seizure-related death in mice lacking HCN1 channels. 20384728 2010
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1 		0.300 Biomarker phenotype CTD_human GLUT-1 deficiency syndrome caused by haploinsufficiency of the blood-brain barrier hexose carrier. 9462754 1998
Entrez Id: 7249
Gene Symbol: TSC2
TSC2 		0.300 Biomarker phenotype CTD_human Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia. 28215400 2017
Entrez Id: 1128
Gene Symbol: CHRM1
CHRM1 		0.300 Biomarker phenotype CTD_human The role of muscarinic acetylcholine receptor-mediated activation of extracellular signal-regulated kinase 1/2 in pilocarpine-induced seizures. 12091480 2002
Entrez Id: 328
Gene Symbol: APEX1
APEX1 		0.300 Biomarker phenotype CTD_human Mitochondrial DNA damage and the involvement of antioxidant defense and repair system in hippocampi of rats with chronic seizures. 20446108 2010
Entrez Id: 57468
Gene Symbol: SLC12A5
SLC12A5 		0.300 Biomarker phenotype CTD_human A thallium transport FLIPR-based assay for the identification of KCC2-positive modulators. 20086212 2010
Entrez Id: 4852
Gene Symbol: NPY
NPY 		0.300 Biomarker phenotype CTD_human Seizure susceptibility of neuropeptide-Y null mutant mice in amygdala kindling and chemical-induced seizure models. 15451008 2004
Entrez Id: 5443
Gene Symbol: POMC
POMC 		0.300 Biomarker phenotype CTD_human [Modalities and side effects of ACTH therapy of diffuse epilepsy in children]. 6324019 1984
Entrez Id: 147
Gene Symbol: ADRA1B
ADRA1B 		0.300 Biomarker phenotype CTD_human Lack of alpha 1b-adrenergic receptor protects against epileptic seizures. 19125850 2009
Entrez Id: 5020
Gene Symbol: OXT
OXT 		0.300 Biomarker phenotype CTD_human Water intoxication and hyponatremic encephalopathy from the use of an oxytocin nasal spray. A case report. 3923190 1985
Entrez Id: 6505
Gene Symbol: SLC1A1
SLC1A1 		0.300 Biomarker phenotype CTD_human Caffeine-induced inhibition of the activity of glutamate transporter type 3 expressed in Xenopus oocytes. 23262392 2013