|
| Entrez Id: |
3064 |
| Gene Symbol: |
HTT |
HTT
|
0.530 |
Biomarker
|
disease |
CTD_human |
Risk factors for the onset and progression of Huntington disease.
|
28111121 |
2017 |
|
| Entrez Id: |
3064 |
| Gene Symbol: |
HTT |
HTT
|
0.530 |
Biomarker
|
disease |
CTD_human |
Functional changes in postsynaptic adenosine A(2A) receptors during early stages of a rat model of Huntington disease.
|
21867705 |
2011 |
|
| Entrez Id: |
3064 |
| Gene Symbol: |
HTT |
HTT
|
0.530 |
Biomarker
|
disease |
CTD_human |
Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease.
|
20929960 |
2011 |
|
| Entrez Id: |
3064 |
| Gene Symbol: |
HTT |
HTT
|
0.530 |
Biomarker
|
disease |
CTD_human |
DNA breakage and induction of DNA damage response proteins precede the appearance of visible mutant huntingtin aggregates.
|
18831068 |
2009 |
|
| Entrez Id: |
3064 |
| Gene Symbol: |
HTT |
HTT
|
0.530 |
Biomarker
|
disease |
CTD_human |
Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases.
|
19476553 |
2009 |
|
| Entrez Id: |
3064 |
| Gene Symbol: |
HTT |
HTT
|
0.530 |
Biomarker
|
disease |
CTD_human |
Allele-specific silencing of mutant Huntington's disease gene.
|
19094060 |
2009 |
|
| Entrez Id: |
3064 |
| Gene Symbol: |
HTT |
HTT
|
0.530 |
Biomarker
|
disease |
CTD_human |
A small-molecule therapeutic lead for Huntington's disease: preclinical pharmacology and efficacy of C2-8 in the R6/2 transgenic mouse.
|
17925440 |
2007 |
|
| Entrez Id: |
3064 |
| Gene Symbol: |
HTT |
HTT
|
0.530 |
GermlineCausalMutation
|
disease |
ORPHANET |
The relationship between CAG repeat length and age of onset differs for Huntington's disease patients with juvenile onset or adult onset.
|
17181545 |
2007 |
|
| Entrez Id: |
3064 |
| Gene Symbol: |
HTT |
HTT
|
0.530 |
Biomarker
|
disease |
CTD_human |
Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
|
17018277 |
2006 |
|
| Entrez Id: |
3064 |
| Gene Symbol: |
HTT |
HTT
|
0.530 |
Biomarker
|
disease |
CTD_human |
Early behavioral deficits in R6/2 mice suitable for use in preclinical drug testing.
|
16137562 |
2005 |
|
| Entrez Id: |
3064 |
| Gene Symbol: |
HTT |
HTT
|
0.530 |
Biomarker
|
disease |
CTD_human |
Molecular mediators, environmental modulators and experience-dependent synaptic dysfunction in Huntington's disease.
|
15218539 |
2004 |
|
| Entrez Id: |
3064 |
| Gene Symbol: |
HTT |
HTT
|
0.530 |
Biomarker
|
disease |
CTD_human |
Expanded huntingtin activates the c-Jun terminal kinase/c-Jun pathway prior to aggregate formation in striatal neurons in culture.
|
15312898 |
2004 |