Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 79823
Gene Symbol: CAMKMT
CAMKMT 		0.300 Biomarker disease CTD_human Calmodulin Methyltransferase Is Required for Growth, Muscle Strength, Somatosensory Development and Brain Function. 26247364 2015
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Ethosuximide Induces Hippocampal Neurogenesis and Reverses Cognitive Deficits in an Amyloid-β Toxin-induced Alzheimer Rat Model via the Phosphatidylinositol 3-Kinase (PI3K)/Akt/Wnt/β-Catenin Pathway. 26420483 2015
Entrez Id: 9365
Gene Symbol: KL
KL 		0.300 Biomarker disease CTD_human Growth Hormone-Releaser Diet Attenuates Cognitive Dysfunction in Klotho Mutant Mice via Insulin-Like Growth Factor-1 Receptor Activation in a Genetic Aging Model. 25309793 2014
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Notoginsenoside R1 increases neuronal excitability and ameliorates synaptic and memory dysfunction following amyloid elevation. 25213453 2014
Entrez Id: 10367
Gene Symbol: MICU1
MICU1 		0.300 Biomarker disease CTD_human Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling. 24336167 2014
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Protective effects of astragalosides on dexamethasone and Aβ25-35 induced learning and memory impairments due to decrease amyloid precursor protein expression in 12-month male rats. 22484447 2012
Entrez Id: 5447
Gene Symbol: POR
POR 		0.300 Biomarker disease CTD_human PAH particles perturb prenatal processes and phenotypes: protection from deficits in object discrimination afforded by dampening of brain oxidoreductase following in utero exposure to inhaled benzo(a)pyrene. 21987461 2012
Entrez Id: 6855
Gene Symbol: SYP
SYP 		0.300 Biomarker disease CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146 2011
Entrez Id: 3363
Gene Symbol: HTR7
HTR7 		0.300 Biomarker disease CTD_human Optimization of (arylpiperazinylbutyl)oxindoles exhibiting selective 5-HT₇ receptor antagonist activity. 21859099 2011
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7 		0.300 Biomarker disease CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146 2011
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.300 Biomarker disease CTD_human Involvement of interleukin-1 in lipopolysaccaride-induced microglial activation and learning and memory deficits. 21290410 2011
Entrez Id: 57084
Gene Symbol: SLC17A6
SLC17A6 		0.300 Biomarker disease CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146 2011
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.300 Therapeutic disease CTD_human Vascular endothelial growth factor attenuates status epilepticus-induced behavioral impairments in rats. 20801723 2010
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Atorvastatin prevents hippocampal cell death, neuroinflammation and oxidative stress following amyloid-β(1-40) administration in mice: evidence for dissociation between cognitive deficits and neuronal damage. 20816828 2010
Entrez Id: 347
Gene Symbol: APOD
APOD 		0.300 Biomarker disease CTD_human Apolipoprotein D is involved in the mechanisms regulating protection from oxidative stress. 18419796 2008
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Hyposensitivity to the amnesic effects of scopolamine or amyloid beta(25-35) peptide in heterozygous acetylcholinesterase knockout (AChE(+/-)) mice. 18533140 2008
Entrez Id: 43
Gene Symbol: ACHE
ACHE 		0.300 Biomarker disease CTD_human Hyposensitivity to the amnesic effects of scopolamine or amyloid beta(25-35) peptide in heterozygous acetylcholinesterase knockout (AChE(+/-)) mice. 18533140 2008
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.300 Biomarker disease CTD_human The relationship between Bcl-gene expression and learning and memory impairment in chronic aluminum-exposed rats. 17967740 2007
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Effects of a novel cognitive enhancer, spiro[imidazo-[1,2-a]pyridine-3,2-indan]-2(3H)-one (ZSET1446), on learning impairments induced by amyloid-beta1-40 in the rat. 16474004 2006
Entrez Id: 10280
Gene Symbol: SIGMAR1
SIGMAR1 		0.300 Therapeutic disease CTD_human Beneficial effects of the sigma1 receptor agonists igmesine and dehydroepiandrosterone against learning impairments in rats prenatally exposed to cocaine. 15451042 2005
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		0.300 Biomarker disease CTD_human Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse. 12915482 2003
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.300 Biomarker disease CTD_human Peripheral 8-OH-DPAT and scopolamine infused into the frontal cortex produce passive avoidance retention impairments in rats. 12591222 2003
Entrez Id: 5153
Gene Symbol: PDE1B
PDE1B 		0.300 Biomarker disease CTD_human Phosphodiesterase 1B knock-out mice exhibit exaggerated locomotor hyperactivity and DARPP-32 phosphorylation in response to dopamine agonists and display impaired spatial learning. 12077213 2002
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.300 Biomarker disease CTD_human Signatures of hippocampal oxidative stress in aged spatial learning-impaired rodents. 11718997 2001
Entrez Id: 7054
Gene Symbol: TH
TH 		0.300 Biomarker disease CTD_human Dopamine deficiency in mice. 10984662 2000