Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 43
Gene Symbol: ACHE
ACHE 		0.300 Biomarker phenotype CTD_human Release of acetylcholinesterase (AChE) from beta-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice. 18599028 2008
Entrez Id: 9495
Gene Symbol: AKAP5
AKAP5 		0.300 Biomarker phenotype CTD_human Loss of AKAP150 perturbs distinct neuronal processes in mice. 18711127 2008
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Selective activation of α7 nicotinic acetylcholine receptor by PHA-543613 improves Aβ25-35-mediated cognitive deficits in mice. 25881725 2015
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human [Gly14]-Humanin Protects Against Amyloid β Peptide-Induced Impairment of Spatial Learning and Memory in Rats. 27306655 2016
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Inhibition of human high-affinity copper importer Ctr1 orthologous in the nervous system of Drosophila ameliorates Aβ42-induced Alzheimer's disease-like symptoms. 23827522 2013
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Release of acetylcholinesterase (AChE) from beta-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice. 18599028 2008
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Virgin coconut oil (VCO) by normalizing NLRP3 inflammasome showed potential neuroprotective effects in Amyloid-β induced toxicity and high-fat diet fed rat. 29729307 2018
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Lactational exposure of mice to low levels of non-dioxin-like polychlorinated biphenyls increases susceptibility to neuronal stress at a mature age. 26480858 2016
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Atorvastatin prevents hippocampal cell death, neuroinflammation and oxidative stress following amyloid-β(1-40) administration in mice: evidence for dissociation between cognitive deficits and neuronal damage. 20816828 2010
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Beta-amyloid (1-42)-induced learning and memory deficits in mice: involvement of oxidative burdens in the hippocampus and cerebral cortex. 15364477 2004
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Notoginsenoside R1 increases neuronal excitability and ameliorates synaptic and memory dysfunction following amyloid elevation. 25213453 2014
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Intraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice. 19664757 2010
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease. 28448946 2017
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Evaluation of the protective role of melatonin on the behavioral effects of aluminum in a mouse model of Alzheimer's disease. 19770021 2009
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Potassium 2-(1-hydroxypentyl)-benzoate promotes long-term potentiation in Aβ1-42-injected rats and APP/PS1 transgenic mice. 24858312 2014
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Protective effects of astragalosides on dexamethasone and Aβ25-35 induced learning and memory impairments due to decrease amyloid precursor protein expression in 12-month male rats. 22484447 2012
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Ethosuximide Induces Hippocampal Neurogenesis and Reverses Cognitive Deficits in an Amyloid-β Toxin-induced Alzheimer Rat Model via the Phosphatidylinositol 3-Kinase (PI3K)/Akt/Wnt/β-Catenin Pathway. 26420483 2015
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Adenosine A2A receptor blockade prevents memory dysfunction caused by beta-amyloid peptides but not by scopolamine or MK-801. 18191838 2008
Entrez Id: 551
Gene Symbol: AVP
AVP 		0.300 Therapeutic phenotype CTD_human Ameliorative effect of vasopressin-(4-9) through vasopressin V(1A) receptor on scopolamine-induced impairments of rat spatial memory in the eight-arm radial maze. 11553362 2001
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.300 Biomarker phenotype CTD_human The relationship between Bcl-gene expression and learning and memory impairment in chronic aluminum-exposed rats. 17967740 2007
Entrez Id: 50632
Gene Symbol: CALY
CALY 		0.300 Biomarker phenotype CTD_human Increased arterial pressure in mice with overexpression of the ADHD candidate gene calcyon in forebrain. 30753204 2019
Entrez Id: 1105
Gene Symbol: CHD1
CHD1 		0.300 Biomarker phenotype CTD_human Role for Chromatin Remodeling Factor Chd1 in Learning and Memory. 30728766 2019
Entrez Id: 1128
Gene Symbol: CHRM1
CHRM1 		0.300 Biomarker phenotype CTD_human Discovery of a selective allosteric M1 receptor modulator with suitable development properties based on a quinolizidinone carboxylic acid scaffold. 21682298 2011
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7 		0.300 Therapeutic phenotype CTD_human Alpha7 nicotinic acetylcholine receptor activation ameliorates scopolamine-induced behavioural changes in a modified continuous Y-maze task in mice. 18848931 2009
Entrez Id: 1312
Gene Symbol: COMT
COMT 		0.300 Biomarker phenotype CTD_human Generation of membrane-bound catechol-O-methyl transferase deficient mice with disctinct sex dependent behavioral phenotype. 28195063 2016