Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 43
Gene Symbol: ACHE
ACHE 		0.300 Biomarker phenotype CTD_human Release of acetylcholinesterase (AChE) from beta-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice. 18599028 2008
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.300 Biomarker phenotype CTD_human Involvement of interleukin-1 in lipopolysaccaride-induced microglial activation and learning and memory deficits. 21290410 2011
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Atorvastatin prevents hippocampal cell death, neuroinflammation and oxidative stress following amyloid-β(1-40) administration in mice: evidence for dissociation between cognitive deficits and neuronal damage. 20816828 2010
Entrez Id: 4835
Gene Symbol: NQO2
NQO2 		0.300 Biomarker phenotype CTD_human Loss of quinone reductase 2 function selectively facilitates learning behaviors. 20861374 2010
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Beta-amyloid (1-42)-induced learning and memory deficits in mice: involvement of oxidative burdens in the hippocampus and cerebral cortex. 15364477 2004
Entrez Id: 6855
Gene Symbol: SYP
SYP 		0.300 Biomarker phenotype CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146 2011
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Notoginsenoside R1 increases neuronal excitability and ameliorates synaptic and memory dysfunction following amyloid elevation. 25213453 2014
Entrez Id: 4282
Gene Symbol: MIF
MIF 		0.300 Biomarker phenotype CTD_human Macrophage migration inhibitory factor is critically involved in basal and fluoxetine-stimulated adult hippocampal cell proliferation and in anxiety, depression, and memory-related behaviors. 20177408 2011
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.300 Biomarker phenotype CTD_human Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease. 28448946 2017
Entrez Id: 9365
Gene Symbol: KL
KL 		0.300 Biomarker phenotype CTD_human Growth Hormone-Releaser Diet Attenuates Cognitive Dysfunction in Klotho Mutant Mice via Insulin-Like Growth Factor-1 Receptor Activation in a Genetic Aging Model. 25309793 2014
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.300 Biomarker phenotype CTD_human Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau. 12368474 2002
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2 		0.300 Biomarker phenotype CTD_human S-SCAM, a rare copy number variation gene, induces schizophrenia-related endophenotypes in transgenic mouse model. 25653350 2015
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7 		0.300 Biomarker phenotype CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146 2011
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Intraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice. 19664757 2010
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease. 28448946 2017
Entrez Id: 2925
Gene Symbol: GRPR
GRPR 		0.300 Biomarker phenotype CTD_human Impairments of social behavior and memory after neonatal gastrin-releasing peptide receptor blockade in rats: Implications for an animal model of neurodevelopmental disorders. 17097693 2007
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.300 Biomarker phenotype CTD_human Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy. 29860433 2018
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1 		0.300 Biomarker phenotype CTD_human Histocompatibility antigens, aspirin use and cognitive performance in non-demented elderly subjects. 14975599 2004
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4 		0.300 Biomarker phenotype CTD_human "Positron emission tomographic studies of brain dopamine and serotonin transporters in abstinent (+/-)3,4-methylenedioxymethamphetamine (""ecstasy"") users: relationship to cognitive performance." 18661256 2008
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.300 Biomarker phenotype CTD_human Peripheral 8-OH-DPAT and scopolamine infused into the frontal cortex produce passive avoidance retention impairments in rats. 12591222 2003
Entrez Id: 5368
Gene Symbol: PNOC
PNOC 		0.300 Biomarker phenotype CTD_human Nociceptin/orphanin FQ and nocistatin on learning and memory impairment induced by scopolamine in mice. 10401555 1999
Entrez Id: 3363
Gene Symbol: HTR7
HTR7 		0.300 Biomarker phenotype CTD_human Optimization of (arylpiperazinylbutyl)oxindoles exhibiting selective 5-HT₇ receptor antagonist activity. 21859099 2011
Entrez Id: 9495
Gene Symbol: AKAP5
AKAP5 		0.300 Biomarker phenotype CTD_human Loss of AKAP150 perturbs distinct neuronal processes in mice. 18711127 2008
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Evaluation of the protective role of melatonin on the behavioral effects of aluminum in a mouse model of Alzheimer's disease. 19770021 2009
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Potassium 2-(1-hydroxypentyl)-benzoate promotes long-term potentiation in Aβ1-42-injected rats and APP/PS1 transgenic mice. 24858312 2014