Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
0.300 Biomarker disease CTD_human Glucose Metabolism and AMPK Signaling Regulate Dopaminergic Cell Death Induced by Gene (α-Synuclein)-Environment (Paraquat) Interactions. 27324791 2017
Entrez Id: 5368
Gene Symbol: PNOC
PNOC
0.300 Biomarker disease CTD_human Nociceptin/Orphanin FQ Inhibits the Survival and Axon Growth of Midbrain Dopaminergic Neurons Through a p38-MAPK Dependent Mechanism. 26687234 2016
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
0.300 Biomarker disease CTD_human Protective effect of Geraniol on the transgenic Drosophila model of Parkinson's disease. 27026137 2016
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
0.300 Biomarker disease CTD_human Nociceptin/Orphanin FQ Inhibits the Survival and Axon Growth of Midbrain Dopaminergic Neurons Through a p38-MAPK Dependent Mechanism. 26687234 2016
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
0.300 Biomarker disease CTD_human Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells. 26558463 2015
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
0.300 Biomarker disease CTD_human Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells. 26558463 2015
Entrez Id: 55532
Gene Symbol: SLC30A10
SLC30A10
0.300 Biomarker disease CTD_human Manganese-Induced Parkinsonism Is Not Idiopathic Parkinson's Disease: Environmental and Genetic Evidence. 26220508 2015
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
0.300 Biomarker disease CTD_human shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson's disease model. 26075822 2015
Entrez Id: 11315
Gene Symbol: PARK7
PARK7
0.300 Biomarker disease CTD_human Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells. 26558463 2015
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.300 Biomarker disease CTD_human Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells. 26558463 2015
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
0.300 Therapeutic disease CTD_human A recurrent mutation in PARK2 is associated with familial lung cancer. 25640678 2015
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
0.300 Therapeutic disease CTD_human Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells. 26558463 2015
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
0.300 Biomarker disease CTD_human Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells. 26558463 2015
Entrez Id: 27429
Gene Symbol: HTRA2
HTRA2
0.300 Biomarker disease CTD_human Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells. 26558463 2015
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.300 Biomarker disease CTD_human Selective loss of glucocerebrosidase activity in sporadic Parkinson's disease and dementia with Lewy bodies. 25881142 2015
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
0.300 Biomarker disease CTD_human A recurrent mutation in PARK2 is associated with familial lung cancer. 25640678 2015
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.300 Biomarker disease CTD_human Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease. 24441527 2014
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.300 Biomarker disease CTD_human Downregulation of Pink1 influences mitochondrial fusion-fission machinery and sensitizes to neurotoxins in dopaminergic cells. 24792327 2014
Entrez Id: 8854
Gene Symbol: ALDH1A2
ALDH1A2
0.300 Biomarker disease CTD_human Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease. 25045800 2014
Entrez Id: 216
Gene Symbol: ALDH1A1
ALDH1A1
0.300 Biomarker disease CTD_human Benomyl, aldehyde dehydrogenase, DOPAL, and the catecholaldehyde hypothesis for the pathogenesis of Parkinson's disease. 25045800 2014
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
0.300 Biomarker disease CTD_human G2019S LRRK2 mutant fibroblasts from Parkinson's disease patients show increased sensitivity to neurotoxin 1-methyl-4-phenylpyridinium dependent of autophagy. 25017139 2014
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
0.300 Biomarker disease CTD_human Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock-down parkin Drosophila melanogaster exposed to oxidative stress stimuli: implication in autosomal recessive juvenile parkinsonism. 23046578 2013
Entrez Id: 11315
Gene Symbol: PARK7
PARK7
0.300 Biomarker disease CTD_human Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock-down parkin Drosophila melanogaster exposed to oxidative stress stimuli: implication in autosomal recessive juvenile parkinsonism. 23046578 2013
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
0.300 Biomarker disease CTD_human The behavioural and neuropathological impact of intranigral AAV-α-synuclein is exacerbated by systemic infusion of the Parkinson's disease-associated pesticide, rotenone, in rats. 23295396 2013
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
0.300 Biomarker disease CTD_human Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock-down parkin Drosophila melanogaster exposed to oxidative stress stimuli: implication in autosomal recessive juvenile parkinsonism. 23046578 2013