Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
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0.080 | Biomarker | disease | BEFREE | MTAP immunohistochemistry is an accurate and reproducible surrogate for CDKN2A fluorescence in situ hybridization in diagnosis of malignant pleural mesothelioma. | 31231127 | 2020 | ||||
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0.080 | AlteredExpression | disease | BEFREE | We used FISH to examine deletion status of NF2 and 9p21 and immunohistochemistry to examine expression of MTAP and BAP1 in malignant pleural mesothelioma and in reactive mesothelial hyperplasia. | 31231129 | 2020 | ||||
|
0.080 | Biomarker | disease | BEFREE | We examined IHC expression of EZH2, BAP1, and MTAP, and 9p21 FISH in MPM (n = 38) and RMH (n = 29) and analyzed the sensitivity and specificity of each detection assay for distinguishing MPM from RMH. | 30885343 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | A combination of MTAP and BAP1 IHC in cell blocks from pleural effusions appears to be a reliable and useful method for differentiating MPM cells from RMC and can be used in the routine diagnosis of MPM.Cancer Cytopathol 2018;126:54-63.© 2017 American Cancer Society. | 29053210 | 2018 | ||||
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0.080 | Biomarker | disease | BEFREE | MTAP IHC and BAP1 IHC showed 80% and 36.7% sensitivity, respectively, and both showed 100% specificity in differentiating MPM from fibrous pleuritis. | 30429020 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | We examined the expression of the 9p21.3-related proteins (p14, p15, p16, and methylthioadenosine phosphorylase (MTAP)) and BAP1 using IHC in 51 MPM and 25 RMH cases, and assessed their correlation with HD of p16 detected by FISH. | 28213009 | 2017 | ||||
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0.080 | AlteredExpression | disease | BEFREE | In these samples, decreased MTAP expression diagnosed MPM with a sensitivity of 71% and a specificity of 90%. | 22394205 | 2012 | ||||
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0.080 | Biomarker | disease | BEFREE | We used a fluorescent in situ hybridization assay for CDKN2A and MTAP on interphase nuclei in imprints of frozen tissue from 95 cases of pleural mesothelioma. | 12796375 | 2003 |