Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
0.080 Biomarker disease BEFREE MTAP immunohistochemistry is an accurate and reproducible surrogate for CDKN2A fluorescence in situ hybridization in diagnosis of malignant pleural mesothelioma. 31231127 2020
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
0.080 AlteredExpression disease BEFREE We used FISH to examine deletion status of NF2 and 9p21 and immunohistochemistry to examine expression of MTAP and BAP1 in malignant pleural mesothelioma and in reactive mesothelial hyperplasia. 31231129 2020
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
0.080 Biomarker disease BEFREE We examined IHC expression of EZH2, BAP1, and MTAP, and 9p21 FISH in MPM (n = 38) and RMH (n = 29) and analyzed the sensitivity and specificity of each detection assay for distinguishing MPM from RMH. 30885343 2019
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
0.080 Biomarker disease BEFREE A combination of MTAP and BAP1 IHC in cell blocks from pleural effusions appears to be a reliable and useful method for differentiating MPM cells from RMC and can be used in the routine diagnosis of MPM.Cancer Cytopathol 2018;126:54-63.© 2017 American Cancer Society. 29053210 2018
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
0.080 Biomarker disease BEFREE MTAP IHC and BAP1 IHC showed 80% and 36.7% sensitivity, respectively, and both showed 100% specificity in differentiating MPM from fibrous pleuritis. 30429020 2018
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
0.080 Biomarker disease BEFREE We examined the expression of the 9p21.3-related proteins (p14, p15, p16, and methylthioadenosine phosphorylase (MTAP)) and BAP1 using IHC in 51 MPM and 25 RMH cases, and assessed their correlation with HD of p16 detected by FISH. 28213009 2017
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
0.080 AlteredExpression disease BEFREE In these samples, decreased MTAP expression diagnosed MPM with a sensitivity of 71% and a specificity of 90%. 22394205 2012
Entrez Id: 4507
Gene Symbol: MTAP
MTAP
0.080 Biomarker disease BEFREE We used a fluorescent in situ hybridization assay for CDKN2A and MTAP on interphase nuclei in imprints of frozen tissue from 95 cases of pleural mesothelioma. 12796375 2003