Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 Biomarker disease BEFREE Women with histologically confirmed stage I to III invasive breast cancer with estrogen receptor and/or progesterone receptor-positive, HER2/neu-negative receptor status were included. 30852142 2019
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 Biomarker disease BEFREE Comparison of analytical and immunohistochemical performance of progesterone receptor (PR) antibodies with correlation to recurrence of invasive breast cancer treated with endocrine therapy. 29758480 2018
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 AlteredExpression disease BEFREE Therefore, HER-2-positive expression and high Ki-67 expression are predictors of LVI, whereas the expression of ER, PR, CK5/6, EGFR, VEGF, E-cadherin, BCL11A and P53 is not associated with LVI in invasive breast cancer. 29416785 2018
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 Biomarker disease BEFREE The aim of this study was to evaluate the correlation between lymphovascular invasion (LVI) and tumor size, histological grade, and the expression statuses of estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor-2 (HER-2), Ki67, epidermal growth factor receptor (EGFR), vascular endothelial growth factor (VEGF), E-cadherin, and P53 in invasive breast cancer, then establish a prediction model of LVI based on the associated clinicopathological factors.A total of 392 patients with primary invasive breast cancers were enrolled, and their paraffin-embedded tissues were manufactured into the tissue microarray. 30412123 2018
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 Biomarker disease BEFREE Both TBR and SUVmax were significantly correlated with tumor size, incidence of axillary lymph node metastasis, histologic grade, estrogen receptor, progesterone receptor status, and Ki-67.There is a moderate degree of association between TBR of sestamibi and SUVmax of FDG in the invasive breast cancer. 30412075 2018
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 Biomarker disease BEFREE Data of 261 patients who had pathologically confirmed estrogen or progesterone receptor positive invasive breast cancer and had received hormonotherapy for at least a 5-year period were retrospectively analyzed. 30426082 2018
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 Biomarker disease BEFREE Tumor grade and progesterone receptor status predict 21-gene recurrence score in early stage invasive breast carcinoma. 30196425 2018
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 Biomarker disease BEFREE The potential impact of androgens on mammary carcinogenesis has been studied in recent years, and several authors have proposed androgen receptor (AR) IHC testing and targeted antiandrogenic therapy in patients with locally advanced or metastatic triple-negative invasive breast cancer (ie, negative for ER and progesterone receptor and HER-2). 29489512 2018
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 AlteredExpression disease BEFREE The number of PR positive epithelial cells was significantly lower in the group of women with early pregnancy and no subsequent breast cancer compared to the group of nulliparous women with subsequent invasive breast cancer (p = 0.0135). 28423605 2017
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 Biomarker disease BEFREE In this study, using an immunohistochemical method, 272 patients with invasive breast cancer were assessed for the expression of CHIP (graded scores 0-3) and the statuses of biomarkers, such as estrogen receptor (ER), progesterone receptor (PgR), and HER2. 27334118 2016
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 Biomarker disease BEFREE The aim of our study was to compare the estrogen receptor, progesterone receptor and HER2 status as determined by the MapQuant™ test to the routine immuno-histochemical tests in early stage invasive breast cancer in a large comprehensive cancer center. 26829108 2016
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 Biomarker disease BEFREE Clinical outcome and global gene expression data support the existence of the estrogen receptor-negative/progesterone receptor-positive invasive breast cancer phenotype. 26650824 2016
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 Biomarker disease BEFREE We analyzed data from 887 patients with invasive breast cancer and observed that increased Wnt and histone deacetylase (HDAC) activities are associated with estrogen receptor 1 (ESR1) and progesterone receptor (PGR) repression, poor survival, and increased relapse. 27859250 2016
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 Biomarker disease BEFREE Aberrant events and increased variation in imprinted gene DNA methylation, therefore, seem to be frequent in invasive breast cancer and are associated with negative estrogen and progesterone receptor status, without loss of monoallelic expression. 25560175 2015
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 AlteredExpression disease BEFREE Progesterone receptor (PR) expression assessment in early invasive breast cancer remains controversial. 24300977 2014
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 Biomarker disease BEFREE As part of an ongoing quality assurance study, this study evaluated the relationship between Oncotype DX recurrence score and progesterone receptor immunohistochemical result within each Nottingham tumor grade in 1074 cases of invasive breast carcinoma for which an Oncotype DX recurrence score was available. 23060300 2013
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 Biomarker disease BEFREE Estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) status have a strong prognostic and predictive value in invasive breast carcinoma (IBC). 22298467 2012
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 Biomarker disease BEFREE Oestrogen receptor (ER), progesterone receptor (PR), HER2, ki67, p53 and DNA ploidy was performed by image analysis in 162 consecutive IBCAs in women (≤ 40 years) and compared with women ≥ 50 years (100 cases). 22713661 2012
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 AlteredExpression disease BEFREE To evaluate polysomy/amplification of Cep17 in invasive breast cancer with relation to proliferative activity (Ki-67), estrogen receptor, progesterone receptor, and HER2/ neu status, in an attempt to identify a subgroup of patients with a worse prognosis. 22938586 2012
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 Biomarker disease BEFREE The expression of estrogen receptor (ER), progesterone receptor (PR), HER2, HER4, and cystatin M was retrospectively analyzed using immunohistochemistry in 117 patients with ductal carcinoma in situ (DCIS) and in 175 patients with invasive breast cancer (IBC). 21092257 2010
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 GeneticVariation disease BEFREE Increased expression of steroid receptors in LCIS suggests their possible role in the biology of LCIS and, for PR, could influence the predisposition of women diagnosed with LCIS to develop invasive breast carcinoma. 19309393 2009
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 Biomarker disease BEFREE Microsatellite alterations on human chromosome 11 in in situ and invasive breast cancer: a microdissection microsatellite analysis and correlation with p53, ER (estrogen receptor), and PR (progesterone receptor) protein immunoreactivity. 10914818 2000
Entrez Id: 5241
Gene Symbol: PGR
PGR
0.100 AlteredExpression disease BEFREE Nm-23, c-erbB-2, and progesterone receptor expression in invasive breast cancer: correlation with clinicopathologic parameters. 10403901 1999