Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.100 Biomarker disease BEFREE LncRNA HOTAIR functions as a competing endogenous RNA to upregulate SIRT1 by sponging miR-34a in diabetic cardiomyopathy. 30216438 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.100 Biomarker disease BEFREE Tetrahydrocurcumin Ameliorates Diabetic Cardiomyopathy by Attenuating High Glucose-Induced Oxidative Stress and Fibrosis via Activating the SIRT1 Pathway. 31210844 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.100 Biomarker disease BEFREE Blockage of ROS and MAPKs-mediated inflammation via restoring SIRT1 by a new compound LF10 prevents type 1 diabetic cardiomyopathy. 30857947 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.100 Biomarker disease BEFREE Correction to: Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving 'SIRT1 and PGC-1α'. 30119667 2018
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.100 AlteredExpression disease BEFREE Overexpression of miR-22 can attenuate oxidative stress injury in diabetic cardiomyopathy by upregulation of Sirt 1 in vivo and in vitro. 29288528 2018
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.100 Biomarker disease BEFREE Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving 'SIRT1 and PGC-1α'. 30071860 2018
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.100 Biomarker disease BEFREE The aim of our study was to investigate whether 1,25(OH)<sub>2</sub> D<sub>3</sub> can improve diabetic cardiomyopathy through a vitamin D receptor (VDR)-dependent mechanism associated with the PARP1/SIRT1/mTOR pathway. 27561793 2017
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.100 Biomarker disease BEFREE SIRT1 Activation by Resveratrol Alleviates Cardiac Dysfunction via Mitochondrial Regulation in Diabetic Cardiomyopathy Mice. 28883902 2017
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.100 Biomarker disease BEFREE Taken together, our data indicate that SIRT1 plays a critical role in the EGCG-mediated amelioration of I/R injury in diabetic rats, which suggests that EGCG may be a promising dietary supplement for the prevention of diabetic cardiomyopathy. 28714516 2017
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.100 Biomarker disease BEFREE Therefore, SIRT1 attenuate cardiac dysfunction and improve DCP. 28380414 2017