Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2
0.520 AlteredExpression disease BEFREE However, the role of SERCA2 down-regulation in the pathophysiology of diabetes mellitus and diabetic cardiomyopathy is not yet well described. 25270119 2014
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2
0.520 Biomarker disease RGD Sildenafil and FDP-Sr attenuate diabetic cardiomyopathy by suppressing abnormal expression of myocardial CASQ2, FKBP12.6, and SERCA2a in rats. 21441944 2011
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2
0.520 Biomarker disease CTD_human Altered calcium handling is an early sign of streptozotocin-induced diabetic cardiomyopathy. 16685413 2006
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2
0.520 Biomarker disease BEFREE In SERCA2-TGR, contraction amplitude (+48%) and rates of contraction (+34%) and relaxation (+35%) of isolated papillary muscles (PM) were increased (P2+ uptake and SERCA2 protein of SERCA2-TGR were 1.3-fold higher (P2+ uptake, accelerates relaxation and compensates, in part, for depressed Ca2+ uptake in diabetic CM. 12206992 2002