Gene: CCR5 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1234
Gene Symbol: CCR5
CCR5 		0.050 Biomarker disease BEFREE A previous phase I/II trial demonstrated that CCR5 blockade with maraviroc in the first 30days after allo-HCT resulted in a low incidence of early acute GVHD, primarily in visceral organs, but with no impact on late acute or chronic GVHD. 30315941 2019
Entrez Id: 1234
Gene Symbol: CCR5
CCR5 		0.050 AlteredExpression disease BEFREE Downregulation of CCR5 and upregulation of CCR7 expression on donor CD4+ T cells might protect recipients from acute GVHD. 28965881 2018
Entrez Id: 1234
Gene Symbol: CCR5
CCR5 		0.050 GeneticVariation disease BEFREE Studies about association between CCR5 genotype in recipients or donors of allo-HSCT and aGVHD risk were included. 28862353 2017
Entrez Id: 1234
Gene Symbol: CCR5
CCR5 		0.050 Biomarker disease BEFREE However, there was no association of CCL5/CCR5 SNPs with acute GVHD. 17984846 2007
Entrez Id: 1234
Gene Symbol: CCR5
CCR5 		0.050 GeneticVariation disease BEFREE Recipients carrying the CCR5Delta32 allele developed acute GvHD (grades I-IV) less frequently than did patients lacking the CCR5 deletion mutation (11/35 vs. 76/151, p=0.033). 17145599 2006