| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.270 | GeneticVariation | disease | BEFREE | The results of this study indicate that there is a significant association between the HMOX1 (GT)<sub>n</sub> repeat length polymorphism and susceptibility to neonatal hyperbilirubinemia. | 30700176 | 2019 | ||||
|
0.270 | GeneticVariation | disease | BEFREE | Additionally, multivariate logistic regression analysis identified that the mutant genotype of rs4148323 in the UGT1A1 gene, ABO incompatibility, G6PD deficiency, and SS genotype at rs1805173 locus of the HO-1 gene were genetic risk factors of neonatal hyperbilirubinemia. | 30298137 | 2018 | ||||
|
0.270 | GeneticVariation | disease | BEFREE | In this clinical review, we surveyed the role of HO-1 gene promoter polymorphisms in the control of bilirubin production and further considered their role, if any, in the pathophysiology of neonatal hyperbilirubinemia. | 28206992 | 2017 | ||||
|
0.270 | GeneticVariation | disease | BEFREE | G6PD deficiency, short HO-1 promoter GT-repeat and GA at nt211 in UGT1A1 are risk factors of neonatal hyperbilirubinemia. | 27557546 | 2016 | ||||
|
0.270 | GeneticVariation | disease | BEFREE | Short (GT)n repeats of HO-1 gene, c.211G>A variant of UGT1A1 gene, and excessive weight loss were independent risk factors for neonatal hyperbilirubinemia. | 23877636 | 2013 | ||||
|
0.270 | Biomarker | disease | RGD | Targeted suppression of heme oxygenase-1 by small interference RNAs inhibits the production of bilirubin in neonatal rat with hyperbilirubinemia. | 19646271 | 2009 | ||||
|
0.270 | GeneticVariation | disease | BEFREE | Because bilirubin production plays a critical role during the neonatal period, the HO-1 promoter polymorphism may be an important genetic factor for the clinical outcome of neonatal hyperbilirubinemia. | 17325212 | 2007 | ||||
|
0.270 | GeneticVariation | disease | BEFREE | Neonatal hyperbilirubinemia in Japanese neonates: analysis of the heme oxygenase-1 gene and fetal hemoglobin composition in cord blood. | 12736395 | 2003 |