Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 CausalMutation disease CGI
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 GeneticVariation disease BEFREE The incidence of topoisomerase II-alpha genomic alterations in adenocarcinoma of the breast and their relationship to human epidermal growth factor receptor-2 gene amplification: a fluorescence in situ hybridization study. 15891995 2005
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease BEFREE Spheroids of HER2-Positive Breast Adenocarcinoma for Studying Anticancer Immunotoxins In Vitro. 28461972 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease BEFREE Fifty patients with typical infiltrating ductal adenocarcinoma of the breast were studied for amplification of the c-erb B-2 (neu/HER-2) oncogene within the tumor DNA. 1967929 1990
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease BEFREE We report the case of an 82-year-old male patient with a > 8-year history of prostate cancer (PrCa), who developed breast adenocarcinoma (BrCa) (Ki-67+ and negative for ER, PR, PSA and HER2/neu) after prolonged (approximately 7-year) anti-androgen (flutamide) monotherapy for locally advanced PrCa. 15154626 2004
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease BEFREE Patients ≥ 18 years of age with histologically-confirmed HER2-positive adenocarcinoma of the breast (clinical T1-T3, N0-N2, M0), normal left ventricular ejection fraction, and adequate organ function received trastuzumab 6 mg/kg intravenous (I.V.) 25640059 2015
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease BEFREE Fluorescence in situ hybridization (FISH) as primary methodology for the assessment of HER2 Status in adenocarcinoma of the breast: a single institution experience. 18043283 2007
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease BEFREE This observational study was conducted in patients with HER2-positive breast adenocarcinoma ≤1.5 cm who received trastuzumab-based adjuvant treatment in clinical practice. 26103952 2015
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease BEFREE Twenty-six women with newly diagnosed stage II to III histologically or cytologically proven adenocarcinoma of the breast with negative HER2 status were enrolled. 28579139 2017
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease BEFREE We found that recombinant protein 4D5scFv-miniSOG exerts a highly specific photo-induced cytotoxic effect on HER2/neu-positive human breast adenocarcinoma SK-BR-3 cells (IC50= 160 nM). 24312153 2013
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 AlteredExpression disease BEFREE The influence of polysomy 17 on HER2 gene and protein expression in adenocarcinoma of the breast: a fluorescent in situ hybridization, immunohistochemical, and isotopic mRNA in situ hybridization study. 16096413 2005
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 Biomarker disease BEFREE In comparison with activated peripheral blood mononuclear cells (PBMCs) and bulk CD8<sup>+</sup> T cells, HER2-specific CTLs exhibited greater cytotoxicity against the HER2-expressing human breast adenocarcinoma cell line MCF-7 and produced higher levels of IFN-γ in response to tumor cells. 31143180 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 GenomicAlterations disease CGI
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.400 AlteredExpression disease BEFREE GCS overexpression was coincident with HER2 expression (γ2=0.84) in ER-negative breast adenocarcinoma. 21617856 2011