Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
0.390 GeneticVariation phenotype BEFREE Patients with the CYP2E1 variant genotype or Null GSTT1 showed higher risk of presenting DILI (p=0.09; OR: 4.57; 95% CI: 0.75-27.6). 31697922 2020
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
0.390 GeneticVariation phenotype BEFREE Previous studies suggest that individuals who are homozygous-null at the GSTM1 or GSTT1 locus may have an increased risk of environmentally related cancers and drug-induced hepatotoxicity. 30471640 2019
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
0.390 Biomarker phenotype CTD_human Characterization of chemically induced liver injuries using gene co-expression modules. 25226513 2014
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
0.390 GeneticVariation phenotype BEFREE GSTM1 and GSTT1 genetic polymorphisms and risk of anti-tuberculosis drug-induced hepatotoxicity: an updated meta-analysis. 23377313 2013
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
0.390 GeneticVariation phenotype BEFREE GSTM1 and GSTT1 null polymorphisms and susceptibility to anti-tuberculosis drug-induced liver injury: a meta-analysis. 23232001 2013
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
0.390 GeneticVariation phenotype BEFREE CYP2E1, GSTM1 and GSTT1 genetic polymorphisms and susceptibility to antituberculosis drug-induced hepatotoxicity: a nested case-control study. 22335459 2012
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
0.390 GeneticVariation phenotype BEFREE The roles of GSTM1 and GSTT1 null genotypes and other predictors in anti-tuberculosis drug-induced liver injury. 22845549 2012
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
0.390 GeneticVariation phenotype BEFREE Homozygosity for GSTM1 null and/or GSTT1 null alleles also seems to be a risk factor for DILI, with associations described independently for several drugs. 20415545 2010
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
0.390 GeneticVariation phenotype BEFREE The double-null genotype for GSTT1 and GSTM1 might play a role in determining the susceptibility to develop DILI, as a general mechanism that occurs regardless of the type of drug involved, and predominantly in women. 18666253 2008
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
0.390 Biomarker phenotype CTD_human The GSTT1 homozygous null polymorphism may be a risk factor of antituberculosis drug-induced hepatotoxicity in Caucasians. 18397238 2008
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
0.390 Biomarker phenotype CTD_human The double-null genotype for GSTT1 and GSTM1 might play a role in determining the susceptibility to develop DILI, as a general mechanism that occurs regardless of the type of drug involved, and predominantly in women. 18666253 2008
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
0.390 GeneticVariation phenotype BEFREE The GSTT1 homozygous null polymorphism may be a risk factor of antituberculosis drug-induced hepatotoxicity in Caucasians. 18397238 2008