Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8556
Gene Symbol: CDC14A
CDC14A 		0.300 Biomarker phenotype CTD_human CDC14A phosphatase is essential for hearing and male fertility in mouse and human. 29293958 2018
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4 		0.300 Biomarker phenotype CTD_human Crosstalk between BPA and FXRα Signaling Pathways Lead to Alterations of Undifferentiated Germ Cell Homeostasis and Male Fertility Disorders. 30245210 2018
Entrez Id: 2023
Gene Symbol: ENO1
ENO1 		0.300 Biomarker phenotype CTD_human Comparative proteomics reveals the underlying toxicological mechanism of low sperm motility induced by iron ion radiation in mice. 27460355 2016
Entrez Id: 217
Gene Symbol: ALDH2
ALDH2 		0.300 Biomarker phenotype CTD_human Assessment of the reproductive toxicity of inhalation exposure to ethyl tertiary butyl ether in male mice with normal, low active and inactive ALDH2. 24448831 2014
Entrez Id: 581
Gene Symbol: BAX
BAX 		0.300 Biomarker phenotype CTD_human Possible effects of metallosis on spermatozoal apoptotic genes expression in individuals with intramedullary nailing prosthesis. 24723216 2014
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.300 Biomarker phenotype CTD_human Genetic variants in nitric oxide synthase genes and the risk of male infertility in a Chinese population: a case-control study. 25517965 2014
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.300 Biomarker phenotype CTD_human Possible effects of metallosis on spermatozoal apoptotic genes expression in individuals with intramedullary nailing prosthesis. 24723216 2014
Entrez Id: 387712
Gene Symbol: ENO4
ENO4 		0.300 Biomarker phenotype CTD_human Disruption of a spermatogenic cell-specific mouse enolase 4 (eno4) gene causes sperm structural defects and male infertility. 23446454 2013
Entrez Id: 3948
Gene Symbol: LDHC
LDHC 		0.300 Biomarker phenotype CTD_human Glycolysis and mitochondrial respiration in mouse LDHC-null sperm. 23486916 2013
Entrez Id: 83756
Gene Symbol: TAS1R3
TAS1R3 		0.300 Biomarker phenotype CTD_human Furthermore, clofibrate inhibition of humanized TAS1R3 in the genetic background of Tas1r3(-/-), Gnat3(-/-) doubly null mice led to inducible male sterility. 23818598 2013
Entrez Id: 161582
Gene Symbol: DNAAF4
DNAAF4 		0.300 Biomarker phenotype CTD_human DYX1C1 is required for axonemal dynein assembly and ciliary motility. 23872636 2013
Entrez Id: 346562
Gene Symbol: GNAT3
GNAT3 		0.300 Biomarker phenotype CTD_human Furthermore, clofibrate inhibition of humanized TAS1R3 in the genetic background of Tas1r3(-/-), Gnat3(-/-) doubly null mice led to inducible male sterility. 23818598 2013
Entrez Id: 4968
Gene Symbol: OGG1
OGG1 		0.300 Biomarker phenotype CTD_human OGG1 Ser326Cys polymorphism interacts with cigarette smoking to increase oxidative DNA damage in human sperm and the risk of male infertility. 23376476 2013
Entrez Id: 29102
Gene Symbol: DROSHA
DROSHA 		0.300 Biomarker phenotype CTD_human Genetic variants in microRNA biogenesis pathway genes are associated with semen quality in a Han-Chinese population. 22381205 2012
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.300 Biomarker phenotype CTD_human Genetic variants in TP53 and MDM2 associated with male infertility in Chinese population. 22773013 2012
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.300 Biomarker phenotype CTD_human Genetic variants in antioxidant genes are associated with sperm DNA damage and risk of male infertility in a Chinese population. 22206979 2012
Entrez Id: 1831
Gene Symbol: TSC22D3
TSC22D3 		0.300 Biomarker phenotype CTD_human The glucocorticoid-induced leucine zipper (gilz/Tsc22d3-2) gene locus plays a crucial role in male fertility. 22556341 2012
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.300 Biomarker phenotype CTD_human Transactivating function (AF) 2-mediated AF-1 activity of estrogen receptor α is crucial to maintain male reproductive tract function. 23213263 2012
Entrez Id: 5444
Gene Symbol: PON1
PON1 		0.300 Biomarker phenotype CTD_human Genetic variants in antioxidant genes are associated with sperm DNA damage and risk of male infertility in a Chinese population. 22206979 2012
Entrez Id: 339345
Gene Symbol: NANOS2
NANOS2 		0.300 Biomarker phenotype CTD_human Rhox13 is translated in premeiotic germ cells in male and female mice and is regulated by NANOS2 in the male. 22190708 2012
Entrez Id: 4193
Gene Symbol: MDM2
MDM2 		0.300 Biomarker phenotype CTD_human Genetic variants in TP53 and MDM2 associated with male infertility in Chinese population. 22773013 2012
Entrez Id: 3948
Gene Symbol: LDHC
LDHC 		0.300 Biomarker phenotype CTD_human Lactate dehydrogenase C and energy metabolism in mouse sperm. 21565994 2011
Entrez Id: 5444
Gene Symbol: PON1
PON1 		0.300 Biomarker phenotype CTD_human Association between male infertility and genetic variability at the PON1/2 and GSTM1/T1 gene loci. 21561808 2011
Entrez Id: 54898
Gene Symbol: ELOVL2
ELOVL2 		0.300 Biomarker phenotype CTD_human ELOVL2 controls the level of n-6 28:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in mice. 21106902 2011
Entrez Id: 10047
Gene Symbol: CST8
CST8 		0.300 Biomarker phenotype CTD_human Reduced fertility in vitro in mice lacking the cystatin CRES (cystatin-related epididymal spermatogenic): rescue by exposure of spermatozoa to dibutyryl cAMP and isobutylmethylxanthine. 20811015 2011