Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.500 Biomarker disease CTD_human Peroxisome proliferator-activated receptor-gamma agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents. 17394460 2007
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.500 Biomarker disease CTD_human Superoxide dismutase 1 overexpression reduces MCP-1 and MIP-1 alpha expression after transient focal cerebral ischemia. 15829914 2005
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.500 Biomarker disease CTD_mouse Superoxide dismutase 1 overexpression reduces MCP-1 and MIP-1 alpha expression after transient focal cerebral ischemia. 15829914 2005
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.300 Therapeutic disease CTD_human Red blood cell-coupled tissue plasminogen activator prevents impairment of cerebral vasodilatory responses through inhibition of c-Jun-N-terminal kinase and potentiation of p38 mitogen-activated protein kinase after cerebral photothrombosis in the newborn pig. 21037505 2011
Entrez Id: 41
Gene Symbol: ASIC1
ASIC1
0.300 Biomarker disease CTD_human Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. 21307247 2011
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.300 Therapeutic disease CTD_human Time of day, outcome, and response to thrombolytic therapy: the National Institute of Neurological Disorders and Stroke Recombinant Tissue Plasminogen Activator Stroke Trial experience. 20123226 2010
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.300 Therapeutic disease CTD_human [Thrombolysis in acute ischemic stroke in basic hospitals. four cases reports]. 20488584 2010
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.300 Therapeutic disease CTD_human Symptomatic intracerebral hemorrhage among eligible warfarin-treated patients receiving intravenous tissue plasminogen activator for acute ischemic stroke. 20212195 2010
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
0.300 Therapeutic disease CTD_human Lack of association between hyperglycaemia at arrival and clinical outcomes in acute stroke patients treated with tissue plasminogen activator. 20536612 2010
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.300 Biomarker disease CTD_human Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion. 19417757 2009
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
0.300 Biomarker disease CTD_human Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion. 19417757 2009
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.300 Biomarker disease CTD_human Progesterone, BDNF and neuroprotection in the injured CNS. 19922383 2009
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
0.300 Biomarker disease CTD_human Hyperglycemia-enhanced ischemic brain damage in mutant manganese SOD mice is associated with suppression of HIF-1alpha. 19429140 2009
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.300 Biomarker disease CTD_human Potential role of PUMA in delayed death of hippocampal CA1 neurons after transient global cerebral ischemia. 19095966 2009
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
0.300 Biomarker disease CTD_human Hyperglycemia-enhanced ischemic brain damage in mutant manganese SOD mice is associated with suppression of HIF-1alpha. 19429140 2009
Entrez Id: 4353
Gene Symbol: MPO
MPO
0.300 Biomarker disease CTD_human Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion. 19417757 2009
Entrez Id: 27113
Gene Symbol: BBC3
BBC3
0.300 Biomarker disease CTD_human Potential role of PUMA in delayed death of hippocampal CA1 neurons after transient global cerebral ischemia. 19095966 2009
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
0.300 Biomarker disease CTD_human Tamoxifen neuroprotection in cerebral ischemia involves attenuation of kinase activation and superoxide production and potentiation of mitochondrial superoxide dismutase. 17901229 2008
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
0.300 Therapeutic disease CTD_human The role of Akt signaling in oxidative stress mediates NF-kappaB activation in mild transient focal cerebral ischemia. 18628779 2008
Entrez Id: 5925
Gene Symbol: RB1
RB1
0.300 Biomarker disease CTD_human Tamoxifen neuroprotection in cerebral ischemia involves attenuation of kinase activation and superoxide production and potentiation of mitochondrial superoxide dismutase. 17901229 2008
Entrez Id: 120
Gene Symbol: ADD3
ADD3
0.300 Biomarker disease CTD_human Tamoxifen neuroprotection in cerebral ischemia involves attenuation of kinase activation and superoxide production and potentiation of mitochondrial superoxide dismutase. 17901229 2008
Entrez Id: 1128
Gene Symbol: CHRM1
CHRM1
0.300 Biomarker disease CTD_human Benzamide protects delayed neuronal death and behavioural impairment in a mouse model of global cerebral ischemia. 18501976 2008
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
0.300 Biomarker disease CTD_human Tamoxifen neuroprotection in cerebral ischemia involves attenuation of kinase activation and superoxide production and potentiation of mitochondrial superoxide dismutase. 17901229 2008
Entrez Id: 5970
Gene Symbol: RELA
RELA
0.300 Therapeutic disease CTD_human The role of Akt signaling in oxidative stress mediates NF-kappaB activation in mild transient focal cerebral ischemia. 18628779 2008
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1
0.300 Biomarker disease CTD_human Tamoxifen neuroprotection in cerebral ischemia involves attenuation of kinase activation and superoxide production and potentiation of mitochondrial superoxide dismutase. 17901229 2008