Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.660 Biomarker disease CTD_human Dual targeting of phosphoinositide 3-kinase and mammalian target of rapamycin using NVP-BEZ235 as a novel therapeutic approach in human ovarian carcinoma. 21372221 2011
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.660 AlteredExpression disease LHGDN decreased protein expressions due to increased MMAC gene mutation in advanced endometriosis and ovarian cancers were not observed; a significant difference in MMAC immunostaining between endometriosis and ovarian endometriod adenocarcinoma was seen 17713092 2007
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.660 GeneticVariation disease BEFREE We aimed to evaluate frequency of PTEN mutation, LOH and expression in ovarian tumors. 16793127 2006
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.660 GeneticVariation disease BEFREE We identified a frequency of molecular alterations in both independent and metastatic tumors, including microsatellite instability (uterine tumors, 50% and 67%, respectively; ovarian tumors, 33% and 67%) and PTEN mutations (uterine tumors, 38% and 100%; ovarian tumors, 33% and 83%) that is higher than that observed in single sporadic tumors. 16021566 2005
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.660 Biomarker disease BEFREE Only few patients with CD and VHLD have any ovarian pathology, but PTEN, the CD gene has been investigated in sporadic ovarian tumors. 12144681 2002
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.660 Biomarker disease BEFREE Our results suggest that the PTEN gene plays an important role in the development of a subset but diverse histological types of ovarian tumors. 10629071 2000
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.660 GeneticVariation disease BEFREE Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors. 9605750 1998
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.660 Biomarker disease HPO
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.660 CausalMutation disease CGI
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.660 GenomicAlterations disease CGI