Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 348
Gene Symbol: APOE
APOE
0.100 Biomarker phenotype BEFREE We investigated whether TLR 9 contributes to the development of vascular inflammation and atherogenesis using apolipoprotein E-deficient ( Apoe <sup>-/-</sup>) mice. 30905257 2019
Entrez Id: 348
Gene Symbol: APOE
APOE
0.100 Biomarker phenotype BEFREE Protease-Activated Receptor-2 Plays a Critical Role in Vascular Inflammation and Atherosclerosis in Apolipoprotein E-Deficient Mice. 29700120 2018
Entrez Id: 348
Gene Symbol: APOE
APOE
0.100 Biomarker phenotype BEFREE Glycyrrhizin, a High-Mobility Group Box 1 Inhibitor, Improves Lipid Metabolism and Suppresses Vascular Inflammation in Apolipoprotein E Knockout Mice. 30650406 2018
Entrez Id: 348
Gene Symbol: APOE
APOE
0.100 Biomarker phenotype BEFREE We investigated the effects of AVE0991 on the spontaneous atherosclerosis in apolipoprotein E (ApoE)-/- mice, in the context of vascular inflammation and plaque stability. 27935022 2017
Entrez Id: 348
Gene Symbol: APOE
APOE
0.100 Biomarker phenotype BEFREE We previously reported that Annexin A5 inhibits inflammatory effects of phospholipids, decreases vascular inflammation and improves vascular function in apolipoprotein E(-/-) mice. 25395618 2015
Entrez Id: 348
Gene Symbol: APOE
APOE
0.100 Biomarker phenotype BEFREE Angptl2 knockout in apolipoprotein E-deficient mice (ApoE(-/-)/Angptl2(-/-)) attenuated atherosclerosis progression by decreasing the number of macrophages infiltrating atheromatous plaques, reducing vascular inflammation. 24526691 2014
Entrez Id: 348
Gene Symbol: APOE
APOE
0.100 GeneticVariation phenotype BEFREE Diabetic atherosclerosis in APOE*4 mice: synergy between lipoprotein metabolism and vascular inflammation. 23204275 2013
Entrez Id: 348
Gene Symbol: APOE
APOE
0.100 GeneticVariation phenotype BEFREE Our results suggest that genetic variation at the apoE locus may impact cardiovascular disease risk through enhanced vascular inflammation. 22632920 2012
Entrez Id: 348
Gene Symbol: APOE
APOE
0.100 Biomarker phenotype BEFREE To investigate whether ginkgolide B (a platelet-activating factor inhibitor) affects vascular inflammation in atherosclerosis-prone apolipoprotein E-deficient (ApoE(-/-)) mice. 22662117 2012
Entrez Id: 348
Gene Symbol: APOE
APOE
0.100 Biomarker phenotype BEFREE Activation of aryl hydrocarbon receptor induces vascular inflammation and promotes atherosclerosis in apolipoprotein E-/- mice. 21441140 2011