Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.070 Biomarker phenotype BEFREE Our findings demonstrate that Dectin-2-mediated induction of CCL2 production by macrophages resident in the aortic root and coronary arteries initiates vascular inflammation in a model of Kawasaki disease, suggesting an important role for the innate immune system in initiating vasculitis. 31169521 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.070 Biomarker phenotype BEFREE The lower levels of VK1 in T2D patients were significantly and inversely correlated with MCP-1 and HOMA-IR, which suggests that VK1 supplementation may reduce the vascular inflammation and insulin resistance in T2D. 29227493 2018
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.070 AlteredExpression phenotype BEFREE In vivo studies indicated that the expression of SIRT1, SIRT6 was decreased and the expression of MCP-1, IL-6 and IL-1β was increased in carotid collar-induced vascular inflammation. 28477980 2017
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.070 Biomarker phenotype BEFREE An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice. 19920349 2009
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.070 Biomarker phenotype BEFREE Induction of RAGE and MCP-1 transcripts in patients with diabetes supports a role of chronic vascular inflammation in macrovascular complications. 15677796 2005
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.070 AlteredExpression phenotype BEFREE To help elucidate the role of calcineurin in vascular inflammation, we infected cultured vascular smooth muscle cells (VSMCs) with an adenovirus construct expressing a constitutively active mutant of calcineurin, and examined its effect on the expression of monocyte chemoattractant protein-1 (MCP-1). 14739159 2004
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.070 AlteredExpression phenotype BEFREE This strategy inhibited early vascular inflammation (monocyte infiltration, increased expression of MCP-1, and inflammatory cytokines) and late neointimal hyperplasia. 12065319 2002