Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4512
Gene Symbol: COX1
COX1
0.030 GeneticVariation disease BEFREE COX-1(rs1330344, rs3842788) and COX-2 rs689466 interacted in SVO, but had no additive effect with ischemic stroke and other subtypes. 31735164 2019
Entrez Id: 4512
Gene Symbol: COX1
COX1
0.030 GeneticVariation disease BEFREE Impacts of COX-1 gene polymorphisms on vascular outcomes in patients with ischemic stroke and treated with aspirin. 24930730 2014
Entrez Id: 4512
Gene Symbol: COX1
COX1
0.030 AlteredExpression disease BEFREE Whereas the role of COX-1 expressed in platelets in acute coronary syndromes and ischemic stroke is definitely established through several large clinical studies with aspirin, the role of COX-2 activity in these settings is still unclear, because this enzyme was characterized only recently (1991) and its inhibitors (coxibs) only became available in 1998. 19485927 2010