However, it is unknown whether the presence of the ADRB2Gln27Glu polymorphism influences neurovascular responses during exercise in patients with acute coronary syndromes (ACS).
We evaluated the association between beta-adrenergic receptor genes (ADRB1 and ADRB2) polymorphism, cardiovascular risk, and acute coronary syndrome (ACS) in individuals from an Arab ethnicity.
Our previously published data indicate that patients prescribed beta-blocker (BB) therapy after an acute coronary syndrome have differential survival associated with their ADRB2 genotypes.
To evaluate the effect of ADRB1 Arg389Gly (1165 CG), Ser49Gly (145 AG), and ADRB2Gly16Arg (46 GA), Gln27Glu (79 CG) genotypes on survival among patients discharged with prescribed beta-blockers after an acute coronary syndrome (ACS).