The aim of this study was to examine the association between MMP1-1607dupG (rs1799750) and MMP3-1171dupA (rs3025058) gene polymorphisms and acute coronary syndromes (ACS) in the form of unstable angina.
Within this context, our aim was to examine whether MMP1, MMP3, and MMP9 gene polymorphisms are associated with susceptibility to acute coronary syndrome (ACS) or angiographic coronary artery disease (CAD).
In conclusion, the MMP-3 5A/6A polymorphism is significantly associated with the occurrence of acute coronary syndrome, MMP-3 activity, and severity of coronary atherosclerosis.