Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.390 Biomarker disease BEFREE The balance between MMP-9 and endogenous inhibitor, tissue inhibitors of matrix metalloproteinase 1 (TIMP-1), is important in acute coronary syndrome (ACS). 29349668 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.390 Biomarker disease BEFREE To investigate whether focal adhesion kinase (FAK) can participate in the secretion of matrix metalloproteinase 9 (MMP9) after CD147 stimulation in THP-1 induced macrophages; thus, to explore the potential treatment perspectives for acute coronary syndrome (ACS).Phorbol-12-myristate-13-acetate (PMA) was used to induce THP-1 cells to differentiate into macrophages. 29563383 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.390 AlteredExpression disease BEFREE Pentraxin 3, long expression in mononuclear cells of patients with acute coronary syndrome: Correlation with C-reactive protein and matrix metalloproteinase-9 levels. 24709882 2014
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.390 Biomarker disease BEFREE Increased peripheral blood MMP-2 and MMP-9 in acute coronary syndrome (ACS) may be useful as noninvasive tests for detection of plaque vulnerability. 24938016 2014
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.390 AlteredExpression disease BEFREE The obtained results permit to conclude that the increased expression of MMP-2 and MMP-9 metalloproteinases and their tissue inhibitor (TIMP-2) is responsible for disturbed equilibrium of the metalloproteinase/tissue inhibitors system and as a consequence, for destabilization of atherosclerotic plaque and occurrence of the acute coronary syndrome in the investigated group of patients. 23793312 2014
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.390 GeneticVariation disease BEFREE Within this context, our aim was to examine whether MMP1, MMP3, and MMP9 gene polymorphisms are associated with susceptibility to acute coronary syndrome (ACS) or angiographic coronary artery disease (CAD). 23377317 2013
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.390 Biomarker disease CTD_human Expression of toll-like receptor 4, tumor necrosis factor- alpha, matrix metalloproteinase-9 and effects of benazepril in patients with acute coronary syndromes. 20981132 2010
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.390 Biomarker disease LHGDN Elevated levels of IL-6, hs-CRP and MMP-9 provide a link between inflammation, matrix degradation and the development and progression of ACS. 17487763 2007
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.390 AlteredExpression disease BEFREE The T allele of the PPARgamma gene might have a protective effect on the progression of CAD and reduce the onset of acute coronary syndrome, which might be associated with the decreased expression of MMP-9 and TNF-alpha in patients with CAD. 17892998 2007
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.390 GeneticVariation disease LHGDN The present findings suggest that the genetic polymorphism in MMP-9 promoter (C-1562-T) is associated with the susceptibility to ACS in the Han population of China. 15952124 2005