Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.700 PosttranslationalModification disease BEFREE This study was performed to investigate the hypermethylation status of the PTEN gene in ovarian cancer. 15072831 2004
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.700 GeneticVariation disease BEFREE In these cases, there is a high frequency of atypia in the endometriosis, and the endometriosis and the associated ovarian carcinoma may show identical PTEN mutations. 15381900 2004
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.700 GeneticVariation disease BEFREE Alterations in beta-catenin and PTEN genes, as well as MSI, are frequent in low-stage ovarian carcinomas of endometrioid type that have a favorable prognosis. 15668893 2004
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.700 Biomarker disease BEFREE PTEN, a tumor suppressor commonly mutated (50%) in endometrial carcinoma, is found mutated in endometrioid carcinoma of the ovary, but not in other forms of ovarian cancer. 11949955 2002
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.700 Biomarker disease BEFREE It is for the purpose of this study to investigate its function and the mechanisms by which PTEN enhances the sensitivity of ovarian cancer to antitumor agents. 12006545 2002
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.700 GeneticVariation disease BEFREE Among several series of ovarian cancers, the frequency of loss of heterozygosity (LOH) of markers flanking and within PTEN, is approximately 30 to 50%, and the somatic intragenic PTEN mutation frequency is <10%. 11395387 2001
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.700 GeneticVariation disease BEFREE PTEN mutations were detected not only in the endometrioid type but also in the serous and mucinous types of ovarian cancer. 10629071 2000
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.700 GeneticVariation disease BEFREE These data indicate that PTEN/MMAC1 mutations are rare in ovarian cancers. 9625810 1998
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.700 GeneticVariation disease BEFREE In two of the five cases of clinically synchronous cancers, identical or progressive PTEN mutations were found in both the endometrial and ovarian cancers, suggesting that the ovarian tumor is a metastasis from the endometrial primary. 9829719 1998
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.700 GeneticVariation disease BEFREE PTEN mutations were not detected in 13 families at high risk of breast and/or ovarian cancer. 9399897 1997
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.700 Biomarker disease HPO
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.700 CausalMutation disease CGI
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.700 GenomicAlterations disease CGI