Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.380 | Biomarker | disease | CTD_human | Identification of recurrent fusion genes across multiple cancer types. | 30705370 | 2019 | ||||
|
0.380 | Biomarker | disease | BEFREE | Mammalian target of rapamycin (mTOR) siRNA (simTOR) co-transfection was performed to verify the role of mTOR in the suppression effect of miR-1271 on ovarian cancer. | 31411791 | 2019 | ||||
|
0.380 | Biomarker | disease | BEFREE | Upregulation of DEPTOR is a positive prognostic marker in ovarian cancer and is increased in response to mTOR pathway inhibition suggesting that it functions as a tumour suppressor gene in endometrioid ovarian carcinoma. | 30387804 | 2019 | ||||
|
0.380 | Biomarker | disease | BEFREE | Likewise, the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway is also a central regulator of the ovarian cancer. | 29401696 | 2018 | ||||
|
0.380 | Biomarker | disease | BEFREE | The mechanistic target of rapamycin (mTOR) level is hyperelevated in a number of tumor types, including ovarian cancer. | 30272366 | 2018 | ||||
|
0.380 | Biomarker | disease | BEFREE | Sphere forming cells (multicellular spheroids) present in malignant ascites of patients with ovarian cancer represent a major impediment to effective treatment. p70 S6 kinase (p70S6K), which is a downstream effector of mammalian target of rapamycin, is frequently hyperactivated in human ovarian cancer. | 25193855 | 2014 | ||||
|
0.380 | Biomarker | disease | BEFREE | The importance of the PI3K/AKT/MTOR pathway in the progression of ovarian cancer. | 23591839 | 2013 | ||||
|
0.380 | AlteredExpression | disease | BEFREE | Our results indicate that there are significant differences in the expression of some of the mTOR-related tumor suppressors and oncogenes which could be associated with the pathogenesis of ovarian cancer. | 21744334 | 2011 | ||||
|
0.380 | Biomarker | disease | BEFREE | A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer. | 20081105 | 2010 | ||||
|
0.380 | Biomarker | disease | CTD_human | Inhibition of glycolysis enhances cisplatin-induced apoptosis in ovarian cancer cells. | 20138251 | 2010 |